Publications by authors named "Kai Yan Yeong"
Rapid SARS-CoV-2 Variants Enzymatic Detection (SAVED) by CRISPR-Cas12a.
Microbiol Spectr
December 2022
The continuous and rapid surge of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants with high transmissibility and evading neutralization is alarming, necessitating expeditious detection of the variants concerned. Here, we report the development of rapid RS-CoV-2 ariants nzymatic etection (SAVED) based on CRISPR-Cas12a targeting of previously crucial variants, including Alpha, Beta, Gamma, Delta, Lambda, Mu, Kappa, and currently circulating variant of concern (VOC) Omicron and its subvariants BA.1, BA.
View Article and Find Full Text PDFArticle Synopsis
- A captive giant panda in Hong Kong was infected with the Influenza A(H1N1)pdm09 virus.
- The viral load was highest on the first day of infection and became undetectable by the fifth day, with the panda developing an antibody response.
- Genome analysis revealed a high similarity (99.3%-99.9%) between the panda's virus and the circulating H1N1 virus in Hong Kong.
Article Synopsis
- Newcastle disease virus (NDV) affects both wild and domestic birds worldwide, and humans exposed to infected birds can experience conjunctivitis and flu-like symptoms.
- This study identified and isolated NDV from a dromedary fetus after an outbreak in nearby pigeons, using next-generation sequencing techniques.
- Genome and phylogenetic analyses confirmed that the identified NDV belongs to sub-genotype VIg and is closely related to pigeon NDVs in Egypt, marking the first report of NDV isolation in dromedaries, and suggesting a need for further research on its role in abortion.
The Sichuan takin inhabits the bamboo forests in the Eastern Himalayas and is considered as a national treasure of China with the highest legal protection and conservation status considered as vulnerable according to The IUCN Red List of Threatened Species. In this study, fecal samples of 71 Sichuan takins were pooled and deep sequenced. Among the 103,553 viral sequences, 21,961 were assigned to mammalian viruses.
View Article and Find Full Text PDF