Factors determining sensitivity and resistance of tumor cells to arsenic trioxide.

Previously, arsenic trioxide showed impressive regression rates of acute promyelocytic leukemia. Here, we investigated molecular determinants of sensitivity and resistance of cell lines of different tumor types towards arsenic trioxide. Arsenic trioxide was the most cytotoxic compound among 8 arsenicals investigated in the NCI cell line panel.

Pharmacogenomic determination of genes associated with sensitivity or resistance of tumor cells to curcumin and curcumin derivatives.

Curcuma longa L. has long been used as a medicinal plant in traditional Chinese medicine against abdominal disorders. Its active constituent curcumin has anti-inflammatory, chemopreventive and cytotoxic properties.

Photonic band gap in thin wire metamaterials.

We investigate the band structure of a class of photonic crystals made from only thin wires. Using a different method, we demonstrate that a complete photonic band gap is possible for such materials. Band gap materials normally consist of space filling dielectric or metal, whereas thin wires occupy a very small fraction of the volume.

Chaos in the relativistic Euler problem.

The Euler problem with two fixed point masses and one moving mass is reconsidered in the light of general relativity. The scattering of a particle by two fixed black holes is shown to be strongly chaotic. Two neutral black holes have been used for the study.