Publications by authors named "Kai Fang"

The generative pre-trained transformer (GPT) is a notable breakthrough in the field of artificial intelligence, as it empowers machines to effectively comprehend and engage in interactions with humans. The GPT exhibits the capacity to enhance inclusivity and accessibility for students with learning disabilities in the context of higher education, hence potentially facilitating substantial advancements in the field. GPT can provide personalized and diverse solutions that successfully cater to the distinct requirements of students with learning disabilities.

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To evaluate the effectiveness of amplification intervention with hearing aids for restoring binaural auditory function in patients with unilateral moderate to severe sensorineural hearing loss. This study selected 30 patients with normal hearing in one ear and moderate to severe sensorineural hearing loss in the other ear. They were fitted with hearing aids for the worse ear and underwent more than half a year and one year of adaptation training.

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Session-based recommendation (SBR) aims to predict the next item a user might click within an ongoing session, without relying on user profiles or historical data. Modern approaches typically use graph networks to learn item embeddings in Euclidean space via graph convolution operations. However, they often struggle to capture the diversity of user interactions within short, hierarchically structured sessions, which is essential for accurate predictions in SBR.

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Purpose: Subretinal fibrosis is an important cause of visual loss in age-related macular degeneration, but its mechanism remains unclear. This study aims to investigate the role of macrophage-to-myofibroblast transition (MMT) in the formation of subretinal fibrosis and assess whether circ_0001103 can regulate the formation of subretinal fibrosis by regulating MMT.

Methods: Subretinal fibrosis was induced in C57BL/6J mice by laser induction.

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Glandular trichomes (GTs) synthesize, store, and secrete diverse specialized metabolites that protect plants against biotic and abiotic stress. The bloom is deposited on the GTs and is perceptible on the surface of the cucumber fruit. Our previous investigation revealed the absence of bloom on the fruit surface in the loss-of-function CsMYB36 plants.

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Forest fires pose a serious threat to the global ecological environment, and the critical steps in reducing the impact of fires are fire warning and real-time monitoring. Traditional monitoring methods, like ground observation and satellite sensing, were limited by monitoring coverage or low spatio-temporal resolution, making it difficult to meet the needs for precise shape of fire sources. Therefore, we propose an accurate and reliable forest fire monitoring segmentation model U3UNet based on UAV vision, which uses a nested U-shaped structure for feature fusion at different scales to retain important feature information.

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The formed optical cavity mode intensively relies on the size and geometry of optical cavity. When the defect or impurity exists inside the cavity, the formed cavity mode will be destroyed. Here, we propose a metacavity consisting of arrays of linear-crossing metamaterials (LCMMs) with abnormal dispersion, where each LCMM offers both the directional propagation channel for all incident angles and the negative refraction across its neighboring LCMMs.

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CO sequestration technologies (CSTs) allow for increased CO emissions without exceeding a chosen temperature limit by creating additional carbon budgets. While these CO sequestration technologies offer low-cost routes to net-zero emissions, namely, the CST benefits, they impede progress to the Sustainable Development Goals, namely, the CST disbenefits. Focusing on China, we assess both the CST disbenefits and benefits in the climate-energy-air-health cascade by an integrated modeling framework.

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Objective: The Triglyceride-glucose Index (TyG) index is a dependable metric for assessing the degree of insulin resistance, serving as a standalone predictor of ischemic stroke risk, but its precise relationship with early neurological deterioration (END) remains incompletely expounded within the context of acute mild ischemic stroke patients. This research is to examine the correlation of the TyG index with END among patients experiencing acute mild ischemic stroke in China.

Methods: This retrospective analysis was conducted to systematically gather data regarding patients experiencing their maiden episode of acute mild ischemic stroke and hospitalized at the Neurology Department of Nanjing Meishan Hospital, located in Nanjing, Jiangsu Province, China, over the period extending from January 2020 to December 2022.

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With the aim of correcting the problem of trajectory tracking control of a flexible joint space manipulator in environments with different gravity, a neural network adaptive inverse control algorithm based on singular perturbation theory is proposed to resist the disturbance caused by system uncertainty. Firstly, the dynamic model of a flexible joint space manipulator with the influence of gravity is established, and then the system is divided into a fast subsystem and a slow subsystem using singular perturbation theory. The velocity feedback control rate is designed for the fast subsystem to suppress the elastic vibration caused by the joint flexibility.

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Extending the depth-of-charge (DoC) of the layered oxide cathode presents an essential route to improve the competitiveness of the Na-ion battery versus the commercialized LiFePO-based Li-ion battery (0.8 CNY/Wh). However, the DoC-dependent boundary between detrimental/irreversible structural distortion and neutral/reversible structure interconversion cannot be clearly distinguished, which is attributed to the ambiguous recognition of correlation among the complex phase transition, local covalent environment evolution, and charge compensation.

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Hospital staff in the COVID-19 local outbreak were facing different situations, their mental status and influencing factors were also different. The aim of this study is to investigate the anxiety and depression of hospital staff and its potential influence factors during the COVID-19 local outbreak. This was a cross-sectional survey based on a hospital with a local outbreak of COVID-19.

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After charging to a high state-of-charge (SoC), layered oxide cathodes exhibit high capacities but suffer from gliding-induced structural distortions caused by deep Li depletion within alkali metal (AM) layers, especially for high-nickel candidates. In this study, we identify the essential structure of the detrimental H3 phase formed at high SoC to be an intergrowth structure characterized by random sequences of the O3 and O1 slabs, where the O3 slabs represent Li-rich layers and the O1 slabs denote Li-depleted (or empty) layers that glide from the O3 slabs. Moreover, we adopt two doping strategies targeting different doping sites to eliminate the formation of Li-vacant O1 slabs.

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The cold-start problem in sequence recommendations presents a critical and challenging issue for portable sensing devices. Existing content-aware approaches often struggle to effectively distinguish the relative importance of content features and typically lack generalizability when processing new data. To address these limitations, we propose a content-aware few-shot meta-learning (CFSM) model to enhance the accuracy of cold-start sequence recommendations.

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As the preferred anode material for sodium-ion batteries, hard carbon (HC) confronts significant obstacles in providing a long and dominant low-voltage plateau to boost the output energy density of full batteries. The critical challenge lies in precisely enhancing the local graphitization degree to minimize Na ad-/chemisorption, while effectively controlling the growth of internal closed nanopores to maximize Na filling. Unfortunately, traditional high-temperature preparation methods struggle to achieve both objectives simultaneously.

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Lung cancer (LC) is the leading cause of cancer-related mortality worldwide. Radiotherapy is the main component of LC treatment; however, its efficacy is often limited by radioresistance development, resulting in unsatisfactory clinical outcomes. Here, we found that LC radiosensitivity is up-regulated by decreased expression of long-chain acyl-CoA synthase 6 (ACSL6) after irradiation.

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Article Synopsis
  • Researchers studied a protein called SLC2A1 to see how it helps some lung cancer cells resist treatment with certain drugs called taxanes.
  • They found that higher levels of SLC2A1 in cancer tissues were linked to worse outcomes for patients, meaning they did not do as well.
  • SLC2A1 caused cancer cells to grow and spread more, and it helped them survive despite the treatment, making it a key factor in how aggressive the cancer can be.
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Colorectal cancer (CRC) is one of the common clinical malignancies and the fourth leading cause of cancer-related death in the world. The tumor microenvironment (TME) plays a crucial role in promoting tumor angiogenesis, and cancer-associated fibroblasts (CAFs) are one of the key components of the tumor microenvironment. However, due to the high heterogeneity of CAFs, elucidating the molecular mechanism of CAF-mediated tumor angiogenesis remained elusive.

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Article Synopsis
  • The study investigates how temperature sensitivity of soil organic matter decomposition (Q) varies between different types of soil organic matter (POM and MAOM) on the Tibetan Plateau.
  • It was found that POM has higher Q values and greater microbial diversity than MAOM, impacting the structure of microbial communities.
  • The research emphasizes the importance of considering the differences in microbial properties between SOM fractions when modeling carbon-climate feedback to improve accuracy in predictions.
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Hard carbon (HC) is a promising anode candidate for Na-ion batteries (NIBs) because of its excellent Na-storage performance, abundance, and low cost. However, a precise understanding of its Na-storage behavior remains elusive. Herein, based on the DO/HSO-based TMS results collected on charged/discharged state HC electrodes, detailed Na-storage mechanisms (the Na-storage states and active sites in different voltage regions), specific SEI dynamic evolution process (formation, rupture, regeneration and loss), and irreversible capacity contribution (dead Na, NaH, etc.

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The impact of climate warming on soil microbes has been well documented, with studies revealing its effects on diversity, community structure and network dynamics. However, the consistency of soil microbial community assembly, particularly in response to diverse plant root exudates under varying temperature conditions, remains an unresolved issue. To address this issue, we employed a growth chamber to integrate temperature and root exudates in a controlled experiment to examine the response of soil bacteria, fungi, and protists.

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Background: Several respiratory infections outbreaks have been observed in mainland China after reduction of non-pharmaceutical interventions. Other countries have seen increases in respiratory infections outside typical seasons post-COVID-19, warranting investigation into underlying causes.

Methods: We established monitoring networks for suspected respiratory infection in 14 tertiary hospitals nationwide.

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Article Synopsis
  • Idiopathic pulmonary fibrosis (IPF) is linked to aging and is characterized by damage to lung epithelial cells, particularly alveolar type II cells (AEC2s) that play a crucial role in lung repair.
  • Research showed downregulation of lipid metabolism-related genes in AEC2s from both IPF patients and older mice with lung injury, which worsens with age and impairs recovery.
  • Targeting lipid metabolism in AEC2s through supplementation or activation of certain receptors can enhance their regenerative capabilities, suggesting a potential therapeutic avenue for treating IPF.
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The fruit neck is an important agronomic trait of cucumber (Cucumis sativus). However, the underlying genes and regulatory mechanisms involved in fruit neck development are poorly understood. We previously identified a cucumber yellow-green peel (ygp) mutant, whose causal gene is MYB DOMAIN PROTEIN 36 (CsMYB36).

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