Evaluation of the performance of generic and original adapalene gel.

Objective: The aim was to evaluate the difference of the behavior between the commercially available generic adapalene gel and original product with Topical Classification System (TCS), and to analyze the effect of changes of excipients on the release behavior.

Significance: Establishing performance assays to understand the impact of formulation variables on the critical quality attributes (CQA) is critical for the quality assessment of semi-solid generic drug.

Methods: release (IVR), permeation (IVP), viscosity, and pH measurement methods for adapalene gels were established and validated.

Action mode of cranberry anthocyanin on physiological and morphological properties of Staphylococcus aureus and its application in cooked meat.

This study researched the action mode of cranberry anthocyanin (CA) against Staphylococcus aureus and the effect of CA on the counts of S. aureus and the quantity of cooked meat during storage. The antibacterial effect was assessed by minimum inhibitory concentration (MIC) and survival populations of S.

Antimicrobial Activity and Mechanism of Action of the Crude Extract against and Potential Application in Cooked Meat.

has been reported to contain some antimicrobial compounds, such as alkaloids, polyphenols, and terpenoids. However, its effect on has been less well researched. Therefore, this study was designed to evaluate the antimicrobial activity and possible mechanism of action of the crude extract (ATCE) against and potential application in cooked meat.

Antibacterial Activity of Olive Oil Polyphenol Extract Against Typhimurium and : Possible Mechanisms.

Polyphenols are a group of active ingredients in olive oil, and have been reported to exhibit antioxidant activity. subsp. serovar Typhimurium ( Typhimurium) and are common foodborne pathogens causing serious infections and food poisoning in humans.

Ocular pharmacokinetic study on baicalin in lens of rabbits following intragastric administration.

Purpose: This paper is to study the pharmacokinetic features of baicalin in lens through observing baicalin's concentration changes in lens of rabbits following intragastric administration.

Methods: Forty-four rabbits were randomly divided into 11 groups. The lens were collected at the beginning without any intragastric administration, and then collected after 15 minutes following intragastric administration of 80 mg/kg baicalin, and continually collected individually after 0.