Publications by authors named "Kaho Hiramatsu"
Am J Clin Pathol
September 2023
Article Synopsis
- The study evaluates the DNA integrity number (DIN) as a measure of DNA quality in clinical next-generation sequencing (NGS) using 166 tumor samples.
- A DIN cutoff of 2.5 effectively predicted analysis success with good sensitivity (84%) and specificity (78%), but lower DIN values were less reliable.
- The introduction of a new metric, the peak/base ratio, showed even better accuracy for predicting successful analysis, indicating a potential improvement in assessing DNA quality for NGS.
