[Vectorial competence of non-teneral Glossina morsitans morsitans (Mall strain) flies infected by Trypanosoma (Nannomonas) congolense IL 1180].

Non-teneral tsetse flies of Glossina morsitans morsitans (strain Mall) about 16 days old were fed, once, on a rat infected by Trypanosoma congolense IL 1180. The global vectorial competence (VC) of these flies was appraised at 0.1035.

[Effect of the number of health meals before an infectious meal on the vectorial competence of Glossina morsitans morsitans infected by Trypanosoma congolense IL 1180].

The purpose of this work was to assess the influence of several healthy meals (0, 1 and 2) prior to the infectious one on the vectorial competence of Glossina morsitans morsitans (Mall). The teneral flies (< 32 h old) of this line were divided into three groups. The tsetse flies of group A received no meal.

Extension of the prophylactic effect of isometamidium against trypanosome infections in cattle using a biodegradable copolymer.

Two trials were carried out in order to compare the prophylactic effect of a subcutaneously implanted sustained release device (SRD) containing a mixture of a biodegradable copolymer, poly(caprolactone-co-L-lactide), and isometamidium (ISMM) with that obtained after intramuscular injection of the drug. In a first experiment under controlled conditions, two groups of cattle were treated with 0.5 mg/kg isometamidium either as a SRD or intramuscularly (i.

[Effect of the intensity of host parasitemia on the vectorial competence of Glossina morsitans Westwood, 1850 (Mall) infected by Trypanosoma (Nannonmonas) congolense IL 1180].

Two groups of teneral flies (aged less than 32 hours) of Glossina morsitans morsitans (Mall) were fed separately on two rats that had been infected with Trypanosoma (Nannomonas) congolense IL 1180, among which one had a low parasitaemia (antilog 5.4-5.7) and the other a high parasitaemia (antilog 7.

Biodegradable polyesters for controlled release of trypanocidal drugs: in vitro and in vivo studies.

Copolymers of epsilon-caprolactone and L-lactide P(CL-LLA), epsilon-caprolactone and D,L-lactide P(CL-DLLA) and epsilon-caprolactone and trimethylene carbonate P(CL-TMC) were synthesized. The composition of comonomers and their sequence lengths were determined by means of 1H and 13C NMR measurements. The effect of the comonomer on the thermal properties was investigated by differential scanning calorimetry (DSC) analysis.

[Vectorial competence of Glossina tachinoides Westwood and Glossina palpalis gambiensis Vanderplank infected by Trypanosoma brucei brucei EATRO 1125].

The vectorial competence (VC) of teneral (less than 32 h) Glossina tachinoides Westwood and G. palpalis gambiensis Vanderplank, fed simultaneously on a guinea-pig infected with Trypanosoma brucei brucei EATRO 1125, was assessed. Statistical analysis of the experimental results revealed that female G.

[Vectorial competence of Glossina palpalis palpalis, Glossina p. gambiensis and Glossina morsitans morsitans flies for a clone of Trypanosoma (Nannomonas) congolense IL 1180].

The authors report on the results of experimental infections of teneral (age < 32 hours) and non-teneral (age between 80 and 96 hours) Glossina palpalis palpalis, G. p. gambiensis and G.

Field evaluation of the prophylactic effect of an isometamidium sustained-release device against trypanosomiasis in cattle.

In order to compare the prophylactic effect provided by a poly(D,L-lactide) sustained-release device (SRD) containing isometamidium (ISMM) with that provided by the classical intramuscular injection of the drug, a field trial was carried out at the Madina Diassa Ranch in Mali. One- to 3-year-old N'Dama cattle were randomly divided into three groups. The first group (n = 42) was treated with ISMM at a dose of 1 mg/kg of body weight, the second group (n = 44) received the same dose of the drug via an SRD, which was subcutaneously implanted in the shoulder region, and the third group (n = 36) was kept as an untreated control group.

Prophylactic effects of isometamidium- and ethidium-sustained release devices against Trypanosoma congolense in cattle.

Two successive experiments were carried out in which three cows were treated by intramuscular injection of either 0.5 mg/kg isometamidium or 1 mg/kg ethidium and compared with another group of three cows which received a subcutaneously implanted sustained release device (SRD) containing the same dose of drug. The prophylactic effect of both drug formulations was evaluated by exposing the animals at monthly intervals to Glossina morsitans morsitans infected with Trypanosoma congolense.

Comparative evaluation of the prophylactic effect of slow release devices containing homidium bromide and isometamidium on Trypanosoma congolense in rabbits.

Two consecutive experiments were carried out to evaluate the prophylactic effect of biodegradable slow release devices (SRD), containing either isometamidium or homidium bromide. Rabbits subcutaneously implanted with SRD, were challenged with different Trypanosoma congolense stocks at regular intervals between 1 and 6.5 months after treatment.

[Experimental infection of Glossina morsitans morsitans (Mall) with Trypanosoma congolense (ZRE/G143/90). Parasite cycle and vector competence in the tsetse fly].

This report presents an experimental study of the life cycle of Trypanosoma congolense (ZRE/G 143/90) in relation to the vectorial competence of Glossina morsitans (Mall). The rate of engorgement at the time of an infectious meal and the mortality before day 15 of the life cycle were not significantly different between male and female flies. The mesocyclic forms of trypanosomes were regularly observed in the proventriculus, crop duct, oesophagus, cibarium and proboscis, except in the crop.

[Standardization and evaluation of a manual salivation method for the detection of Trypanosoma infection in the tsetse fly (Diptera: Glossinidae)].

Two methods of salivation of tsetse flies, namely manual salivation and method of Bruce et al. were simultaneously evaluated on 1,702 male uninfected Glossina palpalis palpalis (Zaire), G. palpalis gambiensis (Bobo-Dioulasso), G.

Evaluation of the efficacy of a slow release device containing homidium bromide in rabbits infected with Trypanosoma congolense.

The subcutaneous implantation of a slow release device (SRD) containing 1 mg kg-1 homidium bromide (Ethidium) protected 95% of the rabbits for at least 3 months against reinfection with different stocks of Trypanosoma congolense. Only 30.8% of the animals, which received the classical intramuscular injection of 1 mg kg-1 homidium bromide, were protected for more than 1 month.

Infectivity of Trypanosoma (Trypanozoon) brucei gambiense for baboons (Papio hamadryas, Papio papio).

In order to study sensitivity or resistance of T.b. gambiense to baboon serum, two species of baboons, P.

[Vectorial capacity of Glossina palpalis gambiensis (Bobo Dioulasso) for Trypanosoma brucei brucei EATRO 1125].

A total of 440 teneral Glossina palpalis gambiensis received one single bloodmeal on a guinea pig infected chronically with Trypanosoma brucei brucei EATRO 1125. Metacyclic infections were present in 11.29% of the flies, in 2.

[Epidemiology of bovine babesiosis in south-western Angola].

An epidemiological survey on bovine babesiosis was carried out in South-Western Angola. Both parasitological and serological methods were used. Use of the packed cell volume (PCV) technique increased up to five times the detection of infected cattle as compared with the thin blood smear method.

Chemoprophylaxis of trypanosomiasis, due to Trypanosoma (Nannomonas) congolense, in rabbits using a slow release device containing homidium bromide.

The prophylactic activity of a subcutaneously implanted slow release device, containing homidium bromide, was assessed in rabbits, challenged with different stocks of T. congolense, and compared with the classical treatment of 1 mg homidium bromide/kg b.w.

[Animal reservoir hosts of Trypanosoma brucei gambiense in Zaire: trypanosome infections in two foci in Bas-Zaire].

The prevalence of Trypanosoma spp. infections in domestic animals was estimated in a forest (Boma) and a savanna (Kimpese) sleeping focus in Bas-Zaire. The miniature anion-exchange centrifugation technique was used to determine the infection rates with T.

[Animal reservoir of Trypanosoma (Trypanozoon) brucei gambiense in Central africa].

The actual available data, from Central as well as from Western Africa, allow us to assert that animals are naturally carriers of T.b. gambiense.

[Mother-transmitted antimalarial immunity. its evolution in child (author's transl)].

The authors report the results of a survey and a longitudinal study of mother-transmitted antimalarial antibodies, conducted through indirect immunofluorescence tests. The data indicate that 16 p. 100 of the new-born and 25 p.