Extract has Antiproliferative and Proapoptotic Effects on Human Lung and Prostate Cancer Cells.

Although several studies have investigated the cytotoxic effects of different species, there has been only limited research into the cytotoxic effect of The purpose of this research was to evaluate the antioxidant properties, phenolic characterization, and cytotoxic effects of on human lung (A549) and prostate (PC-3) cancer cells and the possible mechanisms involved. The antioxidant properties and phenolic characterization of the extract were determined using spectrophotometric methods and RP-HPLC, respectively. The cytotoxic activity of the extract was determined using the MTT assay.

Dimethyl Sulfoxide Extract of Induces S Phase Arrest and Apoptosis in Human Colon Cancer Cells.

Although several studies have investigated the cytotoxic effects of different species, there has been only limited research into the cytotoxic effect of The purpose of this research was to evaluate the phenolic characterization and the cytotoxic effect of on human colon cancer (WiDr) cells and the possible mechanisms involved. Total polyphenolic contents (TPC) and phenolic characterization of the extract were evaluated using the Folin-Cioceltau method and reversed-phase high performance liquid chromatography (RP-HPLC), respectively. The cytotoxic activity of the extract was determined using the methylthiazolyldiphenyl-tetrazolium bromide (MTT) assay.

Cytotoxic effect of extract on human colon cancer cells through repression of telomerase expression.

is a member of the genus that has long been used for medical objectives. Several studies have reported cytotoxic effects of different species, but there has been only limited investigation of the cytotoxic effect of . The purpose of the current study was to examine the potential effect of extract on cell viability, the cell cycle, apoptosis, and the expression of telomerase in human colon cancer (WiDr) cells.

Antiproliferative and apoptotic effect of extract on human prostate cancer cells.

L. belongs to the family and is frequently used in traditional medicine. Numerous studies have investigated the antiproliferative effects of various extracts of different species, but studies involving the cytotoxic effect of extract are very limited.

Morus Rubra Extract Induces Cell Cycle Arrest and Apoptosis in Human Colon Cancer Cells Through Endoplasmic Reticulum Stress and Telomerase.

Many studies have reported cytotoxic effects of different Morus species, but there have been only limited studies on the cytotoxic effect of Morus rubra. The aims of this study were to evaluate the cytotoxic effect of dimethyl sulfoxide extract of M. rubra and to investigate, for the first time, its probable cytotoxic activity in human colon cancer (WiDr) cells, together with the mechanism involved.

Antiproliferative and proapoptotic activity of Turkish propolis on human lung cancer cell line.

Cancer is a heterogeneous disease, two of whose characteristic features are uncontrollable cell proliferation and insufficient apoptosis. Various studies have investigated the antiproliferative effects of propolis, a natural bee product, from different countries, and its cytotoxic effects have been attributed to its polyphenol contents. The purpose of this study was to show the cytotoxic effects, and possible mechanisms involved, of ethanolic extract of Turkish propolis (EEP) on the human lung cancer (A549) cell line.

Effects of Turkish propolis on expression of hOGG-1 and NEIL-1.

Background/aim: Propolis is a bee product with antioxidative, antimutagenic, and other beneficial properties, and it is used as a natural drug. It is rich in polyphenolic compounds. Its composition varies depending on the particular geographical region.

Matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of matrix metalloproteinase (TIMP-1) in patients with relapsing-remitting multiple sclerosis treated with interferon beta.

Objectives: Matrix metalloproteinases (MMPs), particularly MMP-9, facilitate T-cell migration into the central nervous system. They play a key role in the disruption of the blood-brain barrier (BBB) and thus in the pathogenesis of multiple sclerosis. Interferon beta's (IFNbeta) ability to alter the balance between MMP-9 and MMP-9s natural inhibitor, tissue inhibitor of matrix metalloproteinase-1 (TIMP-1), may play a role in stabilizing the BBB.

Plasma fibronectin level and its association with coronary artery disease and carotid intima-media thickness.

Background: The exact relation of fibronectin with coronary atherosclerosis is unknown. The aim of the present study was to examine the association of fibronectin level with presence and extent of coronary artery disease (CAD) and intima-media thickness (IMT) of common carotid artery (CCA).

Design: The IMTs of CCA of 86 patients who underwent coronary angiography were measured; traditional vascular risk factors were also evaluated in these patients.