Publications by authors named "Kaela M Bynoe"
Mol Cancer Ther
February 2021
Article Synopsis
- The study focuses on improving the delivery of cancer treatments using nanotechnology, specifically targeting metastatic tumors in prostate cancer models that lack certain tumor suppressor genes.
- Researchers found that cabozantinib not only treats cancer but also activates neutrophils to help deliver BSA-coated nanoparticles (BSA-NPs) directly to tumors, significantly enhancing their uptake.
- Results showed a substantial increase in BSA-NP accumulation in tumors when combined with cabozantinib, while also reducing delivery to the liver, highlighting a promising approach to improve cancer therapy effectiveness and reduce side effects.
