Publications by authors named "Kaehler Roth"
Article Synopsis
- A study was conducted to evaluate the effectiveness of point-of-care ultrasonography (POCUS) in assessing gastric content in patients prior to upper gastrointestinal (GI) endoscopy.
- The researchers scanned patients' gastric antrum to measure cross-sectional area and assess if the contents were safe or unsafe, correlating these findings with actual gastric fluid aspirated during the procedure.
- Results indicated that while POCUS accurately identified unsafe contents in a small percentage of patients, the correlation between ultrasound measurements and estimated gastric volumes was moderate, suggesting that qualitative assessments can help identify at-risk patients before anesthesia.
Night shift work increases risk of cardiovascular disease associated with an irregular eating schedule. Elevating this risk is the high level of salt intake observed in the typical Western diet. Renal Na excretion has a distinct diurnal pattern, independent of time of intake, yet the interactions between the time of intake and the amount of salt ingested are not clear.
View Article and Find Full Text PDFDiurnal pattern in skin Na and water content is associated with salt-sensitive hypertension in ET receptor-deficient rats.
Am J Physiol Regul Integr Comp Physiol
April 2018
Article Synopsis
- The skin's ability to store sodium (Na) without water is thought to affect salt-sensitive hypertension, which may be connected to endothelin-1 (ET-1) production in the endothelium.
- In a study, rats lacking functional endothelin type B (ET) receptors showed significant increases in blood pressure and changes in skin sodium storage when on a high-salt diet, compared to control rats.
- Although high-salt intake increased both skin sodium and water content in the ET-def rats, the study suggests that ET receptors primarily influence daily rhythms in skin Na levels and blood pressure, rather than directly affecting nonosmotic sodium storage.
High dietary sodium causes dyssynchrony of the renal molecular clock in rats.
Am J Physiol Renal Physiol
January 2018
Speed JS, Hyndman KA, Roth K, Heimlich JB, Kasztan M, Fox BM, Johnston JG, Becker BK, Jin C, Gamble KL, Young ME, Pollock JS, Pollock DM. High dietary sodium causes dyssynchrony of the renal molecular clock in rats. Am J Physiol Renal Physiol 314: F89-F98, 2018.
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