Publications by authors named "Kadisha Nurgaliyeva"
Background And Objective: Immunoglobulin A (IgA) is the most abundant antibody isotype in the human body, considering its presence on the mucosal surfaces, in addition to the amount circulating in the bloodstream. Serum IgA levels can be variably altered in several pathological settings. However, very few studies specifically investigated serum IgA in Juvenile Idiopathic Arthritis (JIA).
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- Cervical cancer is a significant global health issue, particularly in Kazakhstan, where research on public awareness of HPV and cervical cancer is lacking.
- A study involving 2,272 Kazakhstani women assessed their knowledge of HPV, its link to cervical cancer, and awareness of the HPV vaccine, revealing that over half had been screened for cervical cancer.
- Key factors influencing awareness included age, ethnicity, education, family background, number of deliveries, and menarche, with HPV test and Pap smear results being significant in determining awareness levels.
The diagnosis of Celiac Disease (CD) is first based on the positivity for specific serological markers. The CytoBead CeliAK immunoassay simultaneously measures antibodies (IgA) directed to tissue transglutaminase (tTG), endomysium (EMA), and deamidated gliadin (DG), in addition to providing a control for total IgA levels. The aim of this study is to assess the reliability of this multiplex assay to detect anti-tTG IgA positive patients, compared with a conventional single-parameter enzyme-linked immunosorbent assay (ELISA).
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- A nationwide study analyzed high-risk human papillomavirus (HR-HPV) infections among women visiting gynecological clinics in Kazakhstan, involving 759 participants.
- Results revealed a 39% HPV positivity rate, with the most common strains being HPV-16, HPV-51, HPV-68, and HPV-18.
- The findings suggest that implementing HPV testing alongside cervical cancer screenings could enhance early detection and reduce cervical cancer incidence in the region.