Statistical Analysis on Impact of Image Preprocessing of CT Texture Patterns and Its CT Radiomic Feature Stability: A Phantom Study.

Aim: To examine computed tomography (CT) radiomic feature stability on various texture patterns during pre-processing utilizing the Credence Cartridge Radiomics (CCR) phantom textures.

Materials And Methods: Imaging Biomarker Explorer (IBEX) expansion for the abbreviation IBEX extracted 51 radiomic features of 4 categories from 11 textures image regions of interest (ROI) of the phantom. 19 software pre-processing algorithms processed each CCR phantom ROI.

A Dosimetric Analysis of Modified Volumetric Modulated Arc Therapy for Bone Marrow Sparing Radiotherapy in Cervical Cancer-An alternative Approach to Conventional VMAT.

Background: External beam radiotherapy remains the primary treatment modality in cervical cancer. Nowadays Intensity Modulated Radiotherapy (IMRT) and volumetric modulated arc therapy (VMAT) are increasingly being used to reduce normal tissue toxicity. The drawback of conventional  VMAT is that a considerable volume of pelvic bone marrow receives a low dose.

Second malignant neoplasm risk after craniospinal irradiation in X-ray-based techniques compared to proton therapy.

Cranio-spinal irradiation (CSI) is widely used for treating medulloblastoma cases in children. Radiation-induced second malignancy is of grave concern; especially in children due to their long-life expectancy and higher radiosensitivity of tissues at young age. Several techniques can be employed for CSI including 3DCRT, IMRT, VMAT and tomotherapy.

Dose Calculation Accuracy of AAA and AcurosXB Algorithms for Small Central and Interface Lung Lesions - Verification with Gafchromic Film Dosimetry.

Dose calculation for small field radiotherapy with heterogeneity often involves discrepancies, so that algorithms used by treatment planning systems (TPS) should be evaluated with reference to achieving optimal treatment results. Accuracy of two model based algorithms, AcurosXB (AcXB) and the analytical anisotropic algorithm (AAA) from Eclipse TPS, were here tested. Measurements are made using Gafchromic EBT3 films with indigenously generated lung phantoms irradiated with 6 MV photons.

The effect of influence quantities and detector orientation on small-field patient-specific IMRT QA: comparison of measurements with various ionization chambers.

Intensity-modulated radiation therapy (IMRT) requires a patient-specific quality assurance (QA) program to validate the treatment plan and a high level of dosimetric accuracy in the treatment delivery. Dosimetric verification generally consists of both absolute- and relative-dose measurements in a phantom using ionization chambers. Measurements were carried out with three different ionization chambers (Scanditronix FC 65G, Exradin A18, and PTW PinPoint 31014) to assess the effects of influence quantities such as the stability, pre- and post-irradiation leakage, stem effect, polarity, and ion recombination on the IMRT point-dose verification with two different orientations.

Fluorescence spectral diagnosis of malaria: a preliminary study.

Background: Malaria is the most common disease transmitted by the bite by an infected female anopheles mosquito and caused by the plasmodium parasite. It is mostly prevalent in subtropical regions receiving abundant rain and supporting copious mosquito breeding. This disease is generally detected by the microscopic examination of blood films or antigen based rapid diagnostic test.

Analysis of physical parameters and determination of inflection point for Flattening Filter Free beams in medical linear accelerator.

Background: Medical Linear accelerators manufactured without flattening filters are increasing popular in recent days. The removal of flattening filter results in increased dose rate, reduced mean energy, reduction in head leakage and lateral scattering, which have shown advantageous when used for special treatment procedures.

Aim: This study aims to analyze physical parameters of FFF beams and to determine the inflection point for standardizing the beam flatness and penumbra.