Publications by authors named "Kadi N"

Textile production has doubled in the last 20 years, but only 1% is recycled into new fibers. It is the third largest contributor to water pollution and land use, accounting for 10% of global carbon emissions and 20% of clean water pollution. A key challenge in textile recycling is blended yarns, such as polycotton blends, which consist of polyester and cotton.

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Laparoscopic donor nephrectomy was introduced in 1995 as a means of minimally invasive surgeries that entail kidney extraction from healthy individuals. Since then, it has widely overtaken the traditional open surgical approaches, especially in live donor nephrectomy procedures worldwide. Laparoendoscopic single-site surgery is considered a more optimized surgical approach utilizing a single incision instead of four.

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Article Synopsis
  • The study explores a Fenton-based advanced oxidation process for removing color from reactive-dyed waste cotton, aiming to enhance textile recycling.
  • Test samples of black and blue cotton were treated with a Fenton solution, resulting in significant color removal efficiencies of 61.5% and 72.9%, respectively.
  • Although discoloration was effective, mechanical testing showed decreased tensile strength and thermal stability in the treated fabrics, indicating some degradation of the cotton structure along with the dye removal.
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Background: Renewable materials made using environmentally friendly processes are in high demand as a solution to reduce the pollution created by the fashion industry. In recent years, there has been a growing trend in research on renewable materials focused on bio-based materials derived from fungi.

Results: Recently, fungal cell wall material of a chitosan producing fungus has been wet spun to monofilaments.

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Context.—: Clinical, dermoscopic, and histologic diagnostic criteria may overlap in cases with scarring and nonscarring alopecia, making diagnosis difficult for clinicians and pathologists. New histopathologic discoveries indicate that the cutaneous adnexal structural and homeostatic unit made up of the pilosebaceous unit, eccrine sweat gland coils (ESGCs), and dermal white adipose tissue may have a role in hair follicle renewal.

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Unlabelled: New generation of mission-oriented fabrics meets advanced requirements; such as electrical conductivity, flame retardancy, and anti-bacterial properties. However, sustainability concerns still are on-demand in fabrication of multi-functional fabrics. In this work, we used a bio-based phosphorus molecule (phytic acid, PA) to reinforce flax fabrics against flame via layer-by-layer consecutive surface modification.

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This article explores wood-fiber-based fabrics containing Lyocell yarn in the warp and Spinnova-Lyocell (60%/40%) yarn in the weft, which are used to form unidirectional all-cellulose composites (ACC) through partial dilution in a NaOH-urea solution. The aim is to investigate the role of the yarn orientation in composites, which was conducted by measuring the tensile properties in both the 0° and 90° directions. As a reference, thermoplastic biocomposites were prepared from the same fabrics, with biobased polypropylene (PP) as the matrix.

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All-cellulose composites (ACCs) are manufactured using only cellulose as a raw material. Biobased materials are more sustainable alternatives to the petroleum-based composites that are used in many technical and life-science applications. In this study, an aquatic NaOH-urea solvent system was used to produce sustainable ACCs from wood-based woven textiles with and without the addition of TEMPO-oxidized nanocellulose (at 1 wt.

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Friction between Swedish paper yarn and needles is a limiting factor that-together with the low yarn flexibility-is hindering the knitting and use of paper yarn as a sustainable textile material. To enhance the knittability, paper yarn was coated with textile finishing materials. The effect of six different textile finishing materials used for textiles processing (three different silicone-based, wax, glycerol, and soap) was evaluated.

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Aim: The aim of this study is to present the outcome of kidney transplantation after laparoendoscopic single-site donor nephrectomy (LESS DN) compared with conventional laparoscopic donor nephrectomy (LDN) in a single-center experience.

Methods: This retrospective study compares data from the initial experience with 110 consecutive LESS DN donors and their recipients (group A) with 205 consecutive conventional LDN donors and their recipients (group B).

Results: This study compared 110 LESS DNs completed in an 18-month period with 205 LDNs completed in the immediately preceding 42-month period.

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Red blood cell (RBC) transfusion exposes recipients to hundreds of unmatched minor RBC antigens. This exposure can lead to production of alloantibodies that promote clinically significant hemolytic events. Multiple studies have reported an increased frequency of RBC alloimmunization in patients with autoimmunity.

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Background: Since November 2019, the world has suffered the disastrous consequences of the COVID-19 pandemic. No country has been spared either socially or economically. Given the inevitability of the spread of this virus, researches have been active to understand and to counteract the factors that anticipate its spread.

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: Almost all patients with EGFR-driven lung cancer who are treated with EGFR tyrosine kinase inhibitors (TKI) develop resistance to treatment. A single base (c.2369C>T) transition mutation, T790M, is the most frequent resistance event after first-generation exposure to EGFR TKIs.

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Background: We report our experience with laparoendoscopic single-site donor nephrectomy (LESS DN).

Methods: Retrospective comparative study of data from 200 Consecutive left LESS DN (group A) compared to 205 consecutive conventional laparoscopic donor nephrectomy (LDN) (group B). Standard laparoscopic instruments were used in all patients.

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Article Synopsis
  • Hydroxamate groups are crucial in the biological activity of various natural products, including trichostatin A, which inhibits enzymes by binding zinc(II) ions, and desferrioxamines, which chelate iron using hydroxamate groups.
  • The biosynthesis of desferrioxamines involves a condensation reaction catalyzed by the enzyme DesD, which combines derivatives of hydroxycadaverine.
  • The study identifies the gene responsible for producing the acyl transferase DesC, which modifies hydroxycadaverine with different acyl groups, leading to the variety of desferrioxamines, while also revealing insights about the structure and function of the ferrioxamine B receptor.
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The heat shock protein 70s (HSP70s) are molecular chaperones implicated in many cancers and of significant interest as targets for novel cancer therapies. Several HSP70 inhibitors have been reported, but because the majority have poor physicochemical properties and for many the exact mode of action is poorly understood, more detailed mechanistic and structural insight into ligand-binding to HSP70s is urgently needed. Here we describe the first comprehensive fragment-based inhibitor exploration of an HSP70 enzyme, which yielded an amino-quinazoline fragment that was elaborated to a novel ATP binding site ligand with different physicochemical properties to known adenosine-based HSP70 inhibitors.

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HSP70 is a molecular chaperone and a key component of the heat-shock response. Because of its proposed importance in oncology, this protein has become a popular target for drug discovery, efforts which have as yet brought little success. This study demonstrates that adenosine-derived HSP70 inhibitors potentially bind to the protein with a novel mechanism of action, the stabilization by desolvation of an intramolecular salt-bridge which induces a conformational change in the protein, leading to high affinity ligands.

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Objectives: To compare foot posture in people with and without medial compartment knee osteoarthritis (OA), and to assess association between its abnormalities and medial compartment knee OA.

Methods: We compared the foot posture of patients with clinically and radiographically-confirmed medial compartment knee OA and asymptomatic healthy controls using the foot posture index (FPI), navicular height, and the medial arch.

Results: We included 100 patients and 80 asymptomatic controls.

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Synovitis, acne, pustulosis, hyperostosis, and osteitis syndrome (SAPHO) is a rare disease combining skin, bone, and joint manifestations. Its treatment remains a debated issue in the absence of a valid therapeutic strategy. The experience with tumor necrosis factor alpha (TNF alpha)-blocking agents is still small but encouraging.

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Joint manifestations in scleroderma (Scl) and polymyositis (PM) are dominated by inflammatory arthralgia. Arthritis is less common and preferentially affects the hands, wrists, knees, and ankles. Involvement of the hip has been rarely reported in the literature.

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