Publications by authors named "Kabita Chanania"

Background: Pregnant women are particularly vulnerable to lead toxicity due to increased absorption and decreased elimination of lead from their bodies. The δ-aminolevulinic acid dehydratase (ALAD) gene plays a crucial role in lead metabolism, and its polymorphisms have been implicated in modifying the susceptibility to lead toxicity.

Methods: A cross-sectional study was conducted involving 90 pregnant women and blood samples were collected to measure blood lead levels (BLL) and assessed DNA damage using the comet assay.

View Article and Find Full Text PDF

Background And Aim: With the growth of the world's economy and industrialization, lead (Pb) contamination in the environment has become a major issue on a global scale. Lead is typically linked to unfavorable pregnancy outcomes such as stillbirth, low birth weight preterm, and spontaneous abortion. In this study, we evaluated the blood lead levels of pregnant women and their birth outcomes attending an Indian tertiary care teaching hospital, those who were not exposed to any lead-associated industry or shops.

View Article and Find Full Text PDF
Article Synopsis
  • This study investigates a treatment for heavy menstrual bleeding (menorrhagia) in perimenopausal women with normal or enlarged uteruses, specifically using the drug ormeloxifene.
  • Nearly 900 hysterectomies for menorrhagia are performed annually at the research hospital in Odisha, emphasizing the condition's prevalence.
  • Results show that after one year, 90% of patients treated with ormeloxifene became amenorrheic, experienced significant improvements in endometrial thickness and hemoglobin levels, indicating it as a safe and effective option for managing this issue.
View Article and Find Full Text PDF