Methods and participant characteristics in the Cancer Risk in Vegetarians Consortium: a cross-sectional analysis across 11 prospective studies.

Background: The associations of vegetarian diets with risks for site-specific cancers have not been estimated reliably due to the low number of vegetarians in previous studies. Therefore, the Cancer Risk in Vegetarians Consortium was established. The aim is to describe and compare the baseline characteristics between non-vegetarian and vegetarian diet groups and between the collaborating studies.

Environmental risk factors for reduced kidney function due to undetermined cause in India: an environmental epidemiologic analysis.

Background: An epidemic of chronic kidney disease is occurring in rural communities in low-income and middle-income countries that do not share common kidney disease risk factors such as diabetes and hypertension. This chronic kidney disease of unknown etiology occurs primarily in agricultural communities in Central America and South Asia. Consequently, environmental risk factors including heat stress, heavy metals exposure, and low altitude have been hypothesized as risk factors.

Genetic studies of type 2 diabetes in South Asians: a systematic overview.

Diabetes Mellitus, which affects 366 million people worldwide, is a leading cause of mortality, morbidity, and loss of quality of life. South Asians, comprising 24% of the world's population, suffer a large burden of type 2 diabetes. With intriguing risk phenotypes, unique environmental triggers, and potential genetic predisposition, South Asians offer a valuable resource for investigating the pathophysiology of type 2 diabetes.

Lean people with dysglycemia have a worse metabolic profile than centrally obese people without dysglycemia.

Aim: This study compared metabolic profiles of Asian Indians with normal waist circumference (WC) and dysglycemia versus those with high WC without dysglycemia.

Subjects And Methods: In 2,350 subjects ≥20 years of age from the Chennai Urban Rural Epidemiology Study with full anthropometric and biochemical characterization, high WC was defined as ≥90 cm in males and ≥80 cm in females. Dysglycemia was defined as prediabetes (fasting plasma glucose ≥100 mg/dL and/or 2-h plasma glucose ≥140 mg/dL) or diabetes (fasting plasma glucose ≥126 mg/dL, 2-h plasma glucose ≥200 mg/dL, or treatment for diagnosed diabetes).

Clinical profile of diabetes in the young seen between 1992 and 2009 at a specialist diabetes centre in south India.

Aim: To describe the trends and clinical profile of young diabetic patients (YD) attending a tertiary diabetes centre in south India.

Methods: We reviewed medical records of 2630 YD patients (age at onset ≤25 years) registered between 1992 and 2009. Patients were classified as type 1 diabetes (T1DM), type 2 diabetes (T2DM) gestational diabetes mellitus (GDM) and other types.