Publications by authors named "Kaare Troels Jensen"
Distribution and prognostic value of left ventricular global longitudinal strain in elderly patients with symptomatic severe aortic stenosis undergoing transcatheter aortic valve replacement.
BMC Cardiovasc Disord
December 2020
Article Synopsis
- The study aimed to analyze how common impaired left ventricular global longitudinal strain (LVGLS) is in elderly patients with symptomatic aortic stenosis (AS) undergoing transcatheter aortic valve replacement (TAVR) and its impact on survival.
- Among 411 patients treated over five years, 75% showed impaired LVGLS, while 60% had preserved left ventricular ejection fraction (LVEF).
- Impaired LVGLS greater than -14% was identified as a significant independent predictor of all-cause mortality, indicating that even with preserved LVEF, reduced LVGLS signals a higher risk of death post-procedure.
Aims: Transcatheter valve-in-valve (VIV) implantation is usually discouraged in small surgical tissue valves. We report our first ten cases of fracturing small dysfunctional Mitroflow bioprostheses by high-pressure balloon dilatation to increase the internal diameter of the surgical valve before VIV (BF-VIV).
Methods And Results: BF-VIV was performed in 10 patients (mean age 84±4 years) with failing Mitroflow valves size 19 mm (n=3, threshold of fracture 15 atm) and 21 mm (n=7, threshold of fracture 13 atm).
Background: The use of anthracyclines in treatment of cancer is limited by cardiotoxicity of these compounds and may lead to heart failure. Therefore monitoring of cardiac function is necessary during therapy.
Aim: We evaluated the value of natriuretic peptides (N-terminal pro-atrial natriuretic peptide (N-ANP) and brain natriuretic peptide (BNP)) for monitoring and predicting anthracycline induced cardiotoxicity using radionuclide left ventricular ejection fraction (EF) measurements as reference.