Publications by authors named "Kaĭda S"

Background: The wound healing effects of a specialized amino acid supplement containing calcium beta-hydroxy-beta-methylbutyrate, L-arginine, and L-glutamine (HMB/Arg/Gln) have been reported. This study aimed to investigate the effectiveness of HMB/Arg/Gln in the perioperative management of patients with thoracic esophageal cancer.

Methods: This retrospective cohort study included 131 patients who underwent esophagectomy for thoracic esophageal cancer between January 2016 and November 2023.

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Background: Adjuvant chemotherapy is a standard therapeutic option for resected pancreatic cancer. However, the risk factors for incompletion of adjuvant chemotherapy remain unclear.

Methods: We retrospectively reviewed the medical records of 72 patients who underwent radical pancreatectomy and received S-1 adjuvant chemotherapy for pancreatic cancer.

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Background: Atrio-esophageal fistula is a rare but still a catastrophic complication of radiofrequency ablation of atrial fibrillation. We report a successful case of atrio-esophageal fistula with right posterolateral thoracotomy and right femoral cannulation of cardiopulmonary bypass.

Case Presentation: A 67-year-old man underwent radiofrequency ablation for atrial fibrillation.

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Article Synopsis
  • * Researchers analyzed records of 530 patients, finding that higher bilirubin concentration and drain discharge volume on POD 1 were significantly associated with POBL.
  • * The findings indicate that measuring bilirubin levels in drain fluid can serve as an independent predictor of POBL, aiding in early detection and potentially reducing the need for further interventions.
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  • - A 41-year-old woman experienced anal incontinence after undergoing surgery for a severe perineal laceration during childbirth, leading to a diagnosis of sphincter dysfunction.
  • - The treatment included re-suturing the anal sphincter muscle along with a procedure called perineoplasty, which improved the structure and tone of the perineal area.
  • - Post-surgery, the woman's symptoms of incontinence greatly improved, as evidenced by a significant drop in her incontinence score and better anal function measurements.
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Aim: Antiseptics used at surgical sites are vital to preventing surgical site infections (SSI). In this study, a comparative investigation of the novel antiseptics olanexidine gluconate (OG) and povidone-iodine (PI) was conducted to determine whether OG is more effective than PI against SSI after gastrointestinal surgery.

Methods: This prospective, randomized, single-blind, interventional, single-center study was conducted between August 2018 and February 2021.

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Many cases with esophageal cancer recurrence have worse clinical survival. Treatment with immune checkpoint inhibitor (ICI)has been reported to result in significantly longer overall survival. We investigated the clinical outcomes in 30 patients with esophageal cancer recurrence who underwent neoadjuvant chemotherapy followed by surgery, chemotherapy, and chemoradiotherapy.

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The patient was a 60s male. He underwent esophagectomy and gastric tube reconstruction for Barrett's esophageal cancer( pT3N1M0, pStage Ⅲ). Postoperatively, anastomotic leakage and mediastinitis resulted in septic shock.

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A 70-year-old man was diagnosed with early gastric cancer with ulcerative findings. Endoscopic submucosal dissection as an absolute indication was performed, and en bloc resection was achieved. Pathological examination revealed a well-differentiated adenocarcinoma, 3 × 2 mm in size, intramucosal, with an ulcerative scar, no lymphovascular invasion, and a tumor-free margin.

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Purpose: This study aimed to investigate the risk factors for re-drainage in patients with early drain removal after pancreaticoduodenectomy (PD).

Methods: This study retrospectively analyzed 114 patients who underwent PD and prophylactic drain removal on postoperative day (POD) 4 between January 2012 and March 2021. We analyzed the risk factors for re-drainage according to various factors.

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Article Synopsis
  • * Patients were divided into two groups: one received tolvaptan and spironolactone for five days after surgery, while the control group received standard diuretics based on their condition.
  • * Results showed that tolvaptan significantly reduced pleural effusion and weight gain after five days, but it did not impact the need for pleural aspiration or length of hospital stay.
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Purpose: Candida spp. cause opportunistic infections in conditions of immunodeficiency. Here, we investigated the relationship between colonization of the gastric juice by Candida spp.

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  • The study investigates the link between estimated functional remnant pancreatic volume (eFRPV) and postoperative malnutrition in patients who had pancreaticoduodenectomy (PD).
  • A review of 131 patients' medical records showed that those with severe malnutrition had a significantly lower eFRPV compared to those without malnutrition.
  • Key predictors for severe malnutrition identified were eFRPV ≤55.2 mL·HU, preoperative Onodera’s nutritional index ≤41.9, and body mass index ≤19.1 kg/m², suggesting eFRPV can help assess nutritional status post-surgery.
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  • - The study examined how loss of muscle mass before and after surgery impacts nutrition in patients who had a pancreatectomy, analyzing data from 164 patients between 2011 and 2018.
  • - Results showed that patients who experienced significant muscle loss (high-reduction group) had consistently lower nutritional indicators like albumin and cholinesterase, while there was no notable difference between those with and without preoperative sarcopenia.
  • - The findings suggest that focusing on preserving muscle mass during the surgical process can help maintain better nutritional health after surgery.
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A man in his 80s was referred to our hospital with the chief complaint of perianal erosion. Colonoscopy revealed a peripheral flat lesion in the anal canal. Since immunohistological examination showed positive for CK20 and negative for GCDFP15, we made a preoperative diagnosis of anal canal cancer with Pagetoid spread.

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  • Palliative stoma creation for patients with malignant gastrointestinal obstruction can significantly enhance quality of life and contributes to long-term survival due to advancements in chemotherapy.
  • A study of 24 patients showed that 96% could eat more than a porridge diet post-surgery, with significant improvements in their bowel obstruction scores.
  • However, complications occurred in 42% of patients, with longer hospital stays for those with issues, and long-term survivors were more likely to experience stoma prolapse, highlighting the need for careful surgical techniques and effective post-operative care.
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  • - The debate over surgeries for proximal gastric cancer continues, with total gastrectomy (TG) as the standard approach, while alternatives like proximal gastrectomy (PG) and subtotal esophagectomy are also used in practice.
  • - A study involving 1909 patients examined the types of gastrectomy performed, reconstruction techniques, and factors like stomach size and anti-reflux methods, revealing TG was most common (63.0%), followed by PG (33.4%).
  • - Findings suggest that TG remains the preferred choice in Japanese clinical practice, but the size of the remnant stomach and the location of the esophageal stump significantly influence the reconstruction method after PG.
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Introduction: Post-hepatectomy liver failure (PHLF) is a serious complication associated with major hepatectomies. An accurate prediction of PHLF is necessary to determine the feasibility of major hepatectomy. This study aimed to assess the association between PHLF and preoperative laboratory and computed tomography (CT) findings.

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  • Esophageal cancer surgery often results in significant weight loss and poor nutritional status, prompting a study on home enteral tube feeding supplementation (HES) post-surgery.
  • The study reviewed 67 esophageal cancer patients, with 40 receiving HES after surgery and 27 not receiving it, and assessed their nutritional status over time.
  • Results indicated that those in the HES group experienced less weight loss at both 3 months and 1 year post-surgery compared to the control group, suggesting HES could be beneficial for maintaining weight in these patients.
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Background: There is no consensus amongst comparative studies about the advantages of robotic over laparoscopic surgeries for gastric cancer (GC). We compared invasiveness and lymph node dissection between robotic and laparoscopic gastrectomies (RG and LG).

Methods: We retrospectively reviewed the medical records of 215 consecutive patients with GC who underwent RG or LG with lymphadenectomy from January 2011-December 2020.

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Introduction: This study aimed to provide reference values for the percentage total weight loss during 1 year after laparoscopic sleeve gastrectomy associated with primary response in Japan.

Methods: This multicenter retrospective study comprised 248 patients with severe obesity who underwent laparoscopic sleeve gastrectomy at five institutions in Japan. A percentage total weight loss < 20% at 1 year was defined as primary non-response.

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Objectives: This study aimed to investigate the effect of early administration of delayed-release high-titer pancrelipase.

Methods: The medical records of 120 patients who had undergone pancreatectomy with computed tomography (CT) before and 6 months after surgery were retrospectively reviewed. Delayed-release high-titer pancrelipase were administered daily starting on postoperative day 3, which was defined as the EP group.

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Introduction: Recently, accelerometers have received much attention around the world. This study examined whether the preoperative physical activity level measured by an accelerometer could be a useful predictor of post-hepatectomy complications.

Methods: Between December 2016 and December 2020, the physical activity levels of 185 patients were measured using an accelerometer 3 days before hepatectomy and from postoperative day 1 to 7.

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Background: This study aimed to evaluate the impact of postoperative intra-abdominal infectious complications (PICs) on survival after surgery for gastric cancer.

Methods: A total of 152 patients who underwent curative gastrectomy for gastric cancer were included. The effect of clinicopathological features and PICs on recurrence-free survival (RFS) and overall survival (OS) were investigated.

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Background: Dropped gallstones during laparoscopic cholecystectomy (LC) sometimes induce postoperative infectious complications. However, pleural empyema rarely occurs as a complication of LC.

Case Presentation: We present the case of a 66-year-old woman with right pleural empyema.

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