[A case of amniotic fluid embolism (author's transl)].

A case of lethal amniotic fluid embolism is reported. The microscopic findings are documented and the patho-physiologic course of events is reconstructed. The unsuccessful treatment is compared with recommendations in the literature and critically evaluated.

[Alpha-fetoprotein: its significance in the monitoring of "at risk" pregnancies (author's transl)].

Having plotted a curve showing the normal values of Alpha-Foeto-protein (AFP) concentration in maternal serum and amniotic fluid, its significance in the monitoring of "at risk" pregnancies was examined and critically judged in the light of statements found in the literature. According to the results gained AFP determination in maternal serum or amniotic fluid can only be used with reservation as a monitoring test in "at risk" pregnancies. In particular in Rhesus Incompatibility it was impossible to establish the degree of foetal Haemolysis or to determine the best time for premature induction.

On the regeneration of aortic endothelium at different ages.

In order to study the physiological regeneration of the endothelium, "Hautchen", preparations of aortic endothelium were produced from 15 rabbits of different ages and studied autoradiographically. By determining the number of 3H-thymidine-labelled cells, the mitotic rate and the total number of cells per 0.12 mm2, we arrived at the following conclusions: (1) The mean generation time of endothelial cells increases with advancing age.

[Expermental contribution on the genesis of arteriosclerosis caused by hypertension].

Autoradiographic tests carried out on rats with renal hypertension using 3H-proline resulted in an acclerated collagen synthesis by media cells of aorta and coronary arteries. Electronmicroscopically an increased content of collagen fibers and an enrichment of ruthenium-red-positive substances in the extracellular space were found. The 35S-sulfate-incorporation in aorta and coronary arteries of animals with hypertension is also increased.

Recent experience with a respiratory monitoring system in intensive care.

Computer based instrumentation for continuous monitoring of airway flow, pressure, O2 and CO2 concentration offers an improved noninvasive management technique for patients on mechanical ventilators. Computation of these basic signals provides routinely the following measurements: respiratory rate, tidal volume in and out, minute ventilation, positive end-expiratory pressure, mean airway pressure, inspiration-expiration ra measurements, except for O2 consumption and partially for tco2 production. The system works as a monitor of the respirator (detection of malfunction) and as a monitor of the lung function of the patient.

[A-like effect of a proteinpolysaccharide containing extract from bovine cartilage].

In regard to the undecided immunological role of protein polysaccharides (of the glycosaminoglycan type) for pathogenesis of connective tissue diseases a protein polysaccharide-containing extract from bovine nasal cartilage was tested by the absorption method, precipitation and immunization. An A-like effect of the extract was found.