A Pericyclic Reaction in the Gas Phase Identified by Rotational Spectroscopy: Reaction of a Thiocarboxylic Acid with Sulfur Trioxide.

The reaction of sulfur trioxide (SO) and thiobenzoic acid (CHCOSH) is investigated in the gas phase under supersonic jet conditions. Rotational spectroscopy of the parent and several isotopically substituted derivatives, in conjunction with DFT calculations at the M06-2X/6-311++G(3df,3pd) level of theory, identify the product as thiobenzoic sulfuric anhydride, CHC(=S)OSOOH. Single point CCSD(T)/CBS(D-T)//M06-2X/6-311++G(3df,3pd) calculations place the electronic energy of the product anhydride 114 kJ/mol lower than that of SO+CHCOSH at infinite separation.

Relativistic and quantum electrodynamics effects on NMR shielding tensors of TlX (X = H, F, Cl, Br, I, At) molecules.

The results of relativistic calculations of nuclear magnetic resonance shielding tensors (σ) for the thallium monocation (Tl+), thallium hydride (TlH), and thallium halides (TlF, TlCl, TlBr, TlI, and TlAt) are presented as obtained within a four-component polarization propagator formalism and a two-component linear response approach within the zeroth-order regular approximation. In addition to a detailed analysis of relativistic effects performed in this work, some quantum electrodynamical (QED) effects on those nuclear magnetic resonance shieldings and other small contributions are estimated. A strong dependence of σ(Tl) on the bonding partner is found, together with a very weak dependence of QED effects with them.

Glucotoxicity is mediated by cytoplasmic distribution of RAP1 in pancreatic β-cells.

Diabetes mellitus (DM) is a group of chronic metabolic disorders characterized by persistent hyperglycemia. In our study, we analyzed the level and location of RAP1 changes in the development of β-cell dysfunction induced by glucotoxicity. We employed three pancreatic β-cell lines, namely INS-1, 1.

Development of hybrid electrospun alginate-pulverized moringa composites.

The consideration of biopolymers with natural products offers promising and effective materials with intrinsic and extrinsic properties that are utilized in several applications. Electrospinning is a method known for its unique and efficient performance in developing polymer-based nanofibers with tunable and diverse properties presented as good surface area, morphology, porosity, and fiber diameters during fabrication. In this work, we have developed an electrospun sodium alginate (SA) incorporated with pulverized seed powder (PMO) as a potential natural biosorbent material for water treatment applications.

Serum level of lactadherin (MFGE8) in inflamatory bowel disease.

Objective: Evaluation of serum lactadherin level, its correlation with disease activity and certain biochemical parameters in IBD patients.

Methods: The study involved adult IBD patients, comprising 50 with ulcerative colitis (UC), 68 with Crohn's disease (CD), and 29 healthy controls.

Results: The MFGE8 median concentration was significantly higher in UC versus controls (1914.

Extracorporeal Membrane Oxygenation (VA-ECMO) in Management of Cardiogenic Shock.

Cardiogenic shock is a critical condition of low cardiac output resulting in insufficient systemic perfusion and end-organ dysfunction. Though significant advances have been achieved in reperfusion therapy and mechanical circulatory support, cardiogenic shock continues to be a life-threatening condition associated with a high rate of complications and excessively high patient mortality, reported to be between 35% and 50%. Extracorporeal membrane oxygenation can provide full cardiopulmonary support, has been increasingly used in the last two decades, and can be used to restore systemic end-organ hypoperfusion.

Predictive Risk Factors for Childbirth-Associated Breast Infections in the United States: A 10-Year Perspective.

Infectious mastitis is a common condition that affects up to 33% of lactating women. Several risk factors have been suggested to be strongly associated with breast abscess, nipple infection, and non-purulent mastitis associated with childbirth. In this retrospective cohort study, we gathered data from the National Inpatient Sample (NIS) between 2005 and 2014 and utilized data stratification and backward linear regression to analyze the predictive factors associated with patients hospitalized with breast infection after childbirth, with special consideration of risk factors affecting hospital length of stay (LOS).

Incidental Breast Arterial Calcifications and Assessment of Coronary Artery Disease Risk: A Review and Recommendation.

Coronary artery disease (CAD) continues to be the leading cause of morbidity and mortality in women, contributing to about 20%, or nearly 400,000, of female deaths annually in the United States. Despite their significant burden from CAD, women have been traditionally underrepresented in trials, and therefore, there is still much to be studied regarding the sex-based variations that have been reported regarding the pathophysiology, clinical presentation, efficacy of diagnostic workup, and response to therapy in CAD. Previous studies have reported that breast arterial calcifications, commonly found incidentally on screening mammography, may be associated with risk of CAD; however, there are currently no specific guidelines concerning reporting and quantification practices, as well as further workup recommendations for patients who are found to have vascular calcifications.

Sea spray as a secondary source of chlorinated persistent organic pollutants? - Conclusions from a comparison of seven fresh snowfall events in 2019 and 2021.

Secondary sources of persistent organic pollutants (POPs) gain in importance worldwide as primary sources decline. In this work, we aim to determine whether sea spray may be a secondary source of chlorinated POPs to the terrestrial Arctic, since a similar mechanism was proposed there only for the more water-soluble POPs. To this end, we have determined polychlorinated biphenyls and organochlorine pesticides concentrations in fresh snow and seawater collected in the vicinity of the Polish Polar Station in Hornsund in two sampling periods covering spring 2019 and 2021.

The Microwave Rotational Electric Resonance (RER) Spectrum of Benzothiazole.

The microwave spectra of benzothiazole were measured in the frequency range 2-26.5 GHz using a pulsed molecular jet Fourier transform microwave spectrometer. Hyperfine splittings arising from the quadrupole coupling of the N nucleus were fully resolved and analyzed simultaneously with the rotational frequencies.

Peripartum Cardiomyopathy: Current Understanding of Pathophysiology, Diagnostic Workup, Management, and Outcomes.

Peripartum cardiomyopathy (PPCM) is a relatively rare, potentially life-threatening, idiopathic form of cardiomyopathy that affects previously healthy young women during late pregnancy or in the early postpartum period and is characterized by left ventricular systolic dysfunction in the absence of any other identifiable cardiac causes. Morbidity and mortality with PPCM are remarkably high and it continues to be one of the leading causes of maternal death. Although remarkable advances have been made in our understanding of PPCM in the last few decades, unanswered questions remain regarding its pathophysiology, diagnostic workup, and management options.

Endogenous carbon monoxide (CO) as a modulating factor of molecular biological clock in the hypothalamic structures involved in light transmission in pig and wild boar hybrid during long and short day season.

Mature males of a wild boar-pig crossbreed, during the long and short day season, were used for the study which demonstrates that the chemical light carrier CO regulates the expression of biological clock genes in the hypothalamus via humoral pathways. Autologous blood with experimentally elevated concentrations of endogenous CO (using lamps with white light-emitting diodes) was infused into the ophthalmic venous sinus via the right dorsal nasal vein. Molecular biology methods: qPCR and Western Blot were used to determine the expression of genes and biological clock proteins.

Cyanotic Congenital Heart Disease in Pregnancy: A Review of Pathophysiology and Management.

The advancement of medical treatment and surgical technique, along with the invention of cardiopulmonary bypass, has allowed for long-term survival of patients with cyanotic congenital heart disease (CHD)-with many women with CHD now reaching child-bearing age and wishing to become pregnant. Pregnancy in these women is a major concern as the physiologic adaptations of pregnancy, including an increased circulating volume, increased cardiac output, reduced systemic vascular resistance, and decreased blood pressure, place a substantial load on the cardiovascular system. These changes are essential to meet the increased maternal and fetal metabolic demands and allow for sufficient placental circulation during gestation.

A comparative study based on performance and techno-economic analysis of different strategies for PV-Electrolyzer (green) hydrogen fueling incinerator system.

The integration of hydrogen in the primary energy mix requires a major technological shift in virtually every energy-related application. This study has attempted to investigate the techno-economic solar photovoltaic (PV) integrated water electrolysis and waste incineration system. Three different strategies, i.

Rainwater chemistry composition in Bellsund: Sources of elements and deposition discrepancies in the coastal area (SW Spitsbergen, Svalbard).

Discrepancies in rainfall chemistry in Bellsund were found to be influenced by the orographic barrier and related to the variability in the inflow of air masses as well as to the distance of sampling sites from the sea and thus the extent of sea spray impact. This study covers measurements of rainfall (P) and air temperature (T), physicochemical parameters (pH, specific electrolytic conductivity (SEC), major ions (Cl, NO, SO) and elements (Na, Ca, Mg,K), as well as trace elements (i.a.

A Dialogue in the Medical Perspective-Body Mass and Nutritional Status Disorders during the Development Period.

Eating disorders among children and youth are a serious social problem. The time of development is the starting point in shaping eating patterns. Proper nutrition provides the basis for psychophysical development.

Discovery of a Missing Link: First Observation of the HONO-Water Complex.

The still unexplained daytime HONO concentration in the Earth's atmosphere and the impact of water on the HONO chemistry have been a mystery for decades. Several pathways and many modeling methods have failed to reproduce the atmospheric measurements. We reveal in this study the first spectroscopic observation and characterization of the complex of HONO with water observed through its rotational signature.

Relativistic and QED corrections to one-bond indirect nuclear spin-spin couplings in X and X ions (X = Zn, Cd, Hg).

The indirect spin-spin coupling tensor, J, between mercury nuclei in systems containing this element can be of the order of a few kHz and one of the largest measured. We analyzed the physics behind the electronic mechanisms that contribute to the one- and two-bond couplings J (n = 1, 2). For doing so, we performed calculations for J-couplings in the ionized X and X linear molecules (X = Zn, Cd, Hg) within polarization propagator theory using the random phase approximation and the pure zeroth-order approximation with Dirac-Hartree-Fock and Dirac-Kohn-Sham orbitals, both at four-component and zeroth-order regular approximation levels.

Biomimetically Inspired Highly Homogeneous Hydrophilization of Graphene with Poly(l-DOPA): Toward Electroconductive Coatings from Water-Processable Paints.

Water-based processing of graphene-typically considered as physicochemically incompatible with water in the macroscale-emerges as the key challenge among the central postulates of green nanotechnology. These problematic concerns are derived from the complex nature of graphene in the family of sp-carbon nanoallotropes. Indeed, nanomaterials hidden under the common "graphene" signboard are very rich in morphological and physicochemical variants.

Relationships between the Perception of Footwear Comfort and the Fear of Falls in People at the Early Period of Old Age.

Objective: The present study aimed to analyze the relationships between the perceptions of footwear comfort with fear of falls in younger-old women and men. Participants: the population sample involved 100 free-living community dwellers aged 65−74. Design: the Falls Efficacy Scale-International and a visual analogue scale to assess perception of footwear comfort were used as research tools.

Effects of supplemental flaxseed on the ovarian and uterine functions of adult cycling mice.

Dietary fatty acids (FA) have an effect on animal reproduction. The purpose of the study was to find out how supplemental flaxseed can modulate the FA metabolism and how FA can influence the release of ovarian hormones and functions of the uteri through the modulation of their specific receptors. Cycling mice were fed a basal diet (control) and basal diet fortified with 10% flaxseed for 6 weeks to examine its influence on the structure and function of the ovaries and uteri, and serum levels of FA.