Carbon Nanostructured Immunosensing of Anti-SARS-CoV-2 S-Protein Antibodies.

The rampant spread and death rate of the recent coronavirus pandemic related to the SARS-CoV-2 respiratory virus have underscored the critical need for affordable, portable virus diagnostics, particularly in resource-limited settings. Moreover, efficient and timely monitoring of vaccine efficacy is needed to prevent future widespread infections. Electrochemical immunosensing poses an effective alternative to conventional molecular spectroscopic approaches, offering rapid, cost-effective, sensitive, and portable electroanalysis of disease biomarkers and antibodies; however, efforts to improve binding efficiency and sensitivity are still being investigated.

Risk rates of workplace accidents in Brazil: effect of the Accidental Prevention Factor (APF)?

Historically, the conflict of interests between employers and workers obliged the State to assume the role of regulating this relationship, instituting laws and overseeing the application of health and safety standards at work. The Accident Prevention Factor (FAP) is one of these guidelines. This article aims to analyze the correlations between the FAP and the risk rate for occupational accidents in Brazil in the period between 2006 and 2016.

Good for the Self: Self-Compassion and Other Self-Related Constructs in Relation to Symptoms of Anxiety and Depression in Non-clinical Youths.

This study examined relationships among self-compassion, self-esteem, and self-efficacy and symptoms of anxiety disorders and depression in a sample of 132 non-clinical adolescents aged 12-17 years. The results first of all indicated that the Shortened Self-Compassion Scale for Adolescents was reliable (i.e.

In vivo measurements of lead in bone at four anatomical sites: long term occupational and consequent endogenous exposure.

Measurements of bone lead concentrations in the tibia, wrist, sternum, and calcaneus were performed in vivo by x ray fluorescence on active and retired lead workers from two acid battery factories, office personnel in the two factories under study, and control subjects. Altogether 171 persons were included. Lead concentrations in the tibia and ulna (representative of cortical bone) appeared to behave similarly with respect to time but the ulnar measurement was much less precise.

[Uranitis circinata in Reiter's disease. Therapy with etretinate (Tigason)].

Lesions analogous to the balanitis circinata on the mucous membrane of the palate are reported in two males. Tigason quickly improved the skin lesions, mucous membrane lesions and nail lesions.

Glucocorticosteroids in renal transplantation. II. Impact of high- versus low-dose postoperative methylprednisolone administration on graft survival and on the frequency and type of complications.

In a previous clinical trial we demonstrated that, by increasing the postoperative administration of methylprednisolone from 1.0 to 3.5 mg/kg/day, the onset of the first inflammatory rejection episode was significantly delayed and the size of the inflammation was reduced.

[Treatment of severe pruritus in dialysis patients with selective UV-phototherapy (SUP)].

The beneficial effect of ultraviolet phototherapy (SUP) on uremic pruritus was studied. 16 patients were treated. 14 patients improved after a course of five to 24 UVB exposures.

[Pemphigus vulgaris in childhood].

Histological examination and immunofluorescence technique revealed the clinical diagnosis 'Erythema exudativum multiforme' as a real Pemphigus vulgaris of a 14-year-old boy. Early diagnosis and a large dose therapy of immunosuppressives agents decide on the survival of the patients.

[Experiences with the CO2 laser in dermatology].

During a one-year period of treatment, the authors found indications for (hemangioma, tattoos, viral warts) and limits of CO2 laser therapy (nevus flammeus, keloid).

Early neurotoxic effects of occupational lead exposure: a prospective study.

A prospective follow-up study focusing on workers who entered a battery factory was started in 1975. Out of an initial number of 89 workers, 23 were available for the 1-yr, 15 for the 2-yr and 10 for the 4-yr re-examination. From an initially larger non-exposed reference group (N = 34), 23 were matched with respect to age, sex, and initial nerve conduction velocities and similarly followed.

Ultrasonic scanning after percutaneous renal biopsy.

Renal ultrasonic scanning was performed before and after 57 consecutive kidney biopsies in order to assess the value of this method in the diagnosis of complications. One large and six small perirenal haematomas were found, corresponding to an incidence of 13%. This figure is considerably larger than the incidence found with conventional diagnostic methods, but smaller than with computed tomography.

Long-term 1,25-dihydroxycholecalciferol treatment in renal failure.

1,25-Dihydroxycholecalciferol (1,25-DHCC) was administered to four patients on maintenance hemodialysis and to four patients with renal failure not requiring hemodialysis. Secondary hyperparathyroidism was found in both groups of patients. Before initiation of 1,25-DHCC treatment both groups had serum 1,25-DHCC levels below the normal range (33.

Striated muscle capillaries in uremic patients and in renal transplant recipients.

With the use of light and electron microscopic and morphometric methods, we studied the gastrocnemius muscle capillaries in nine uremic patients and eight renal transplant recipients. Observations of intramuscular microangiopathy, eg, thickening and remnants of the capillary basement membrane (BM) and vacuolation of endothelial cells, were prominent in both patient groups. In morphometric analysis, the mean BM fraction of the total capillary area was larger, and the capillary lumen was smaller, in the uremic patients and in the renal transplant recipients than in the normal control subjects.

Kidney transplantation and tumours.

During the period 1964--1978 700 renal transplants were given to 602 patients. Eight patients had a history of tumour before transplantation. After transplantation six cases with a de novo tumour were found.

Kidney transplantation in patients over 60 years of age.

Between 1972 and the end of 1978 kidney transplantation was performed on 39 patients over 60 years of age. In one case a kidney from a live donor was used. The other patients received cadaver kidneys.

Hyperreninemia, lysozymuria, and erythrocytosis in Fanconi syndrome with medullary cystic kidney.

Adult onset Fanconi syndrome with medullary cystic kidney was diagnosed in a 30-year-old male with muscular weakness, hypokalemia, normal BP, hyperreninemia, and secondary aldosteronism. He also had non-specific aminoaciduria, lysozymuria, and beta 2-microglobulinuria. Urinary concentrating and acidifying capacity was impaired, and both sodium and potassium were lost into the urine.

Fatal renal vasculitis and minimal change glomerulonephritis complicating treatment with penicillamine. Report on two cases.

Two cases with different and not previously described fatal renal complications during treatment with penicillamine are reported. A man with seronegative rheumatoid arthritis with features of systemic lupus erythematosus was treated with penicillamine for six months and developed a mild membranous glomerulonephritis and a severe renal vasculitis leading to uremia and death. A woman with primary biliary cirrhosis was treated with penicillamine for nine months and developed a nephrotic syndrome, the renal biopsy showing minimal change glomerulonephritis.

Vascular access for haemodialysis with autogenous vein graft arteriovenous fistulas.

Nine autogenous vein grafts (AVG) have been used in nine patients to create arteriovenous fistulae for haemodialysis. All the patients lacked vessels for construction of a regular arteriovenous fistula. Three of the AVG failed during dialysis treatment 3, 10 and 14 months respectively following construction.