Acute reversible cardiomyopathy and thromboembolism after cisplatin and 5-fluorouracil chemotherapy--a case report.

Acute development of cardiomyopathy and occlusive thromboembolic events following cisplatin and 5-fluorouracil (5-FU) is rare but frequently lethal. The authors report the successful management of such an event in a 52-year-old man with squamous cell carcinoma of the soft palate. The possible pathophysiological mechanisms are discussed.

Clinical significance of variability of ventricular late potentials detected before discharge in patients after myocardial infarction.

Background: Signal-averaged electrocardiography (SAECG) in patients after myocardial infarction (MI) is widely used to identify patients at risk for ventricular tachycardia (VT) and sudden cardiac death (SCD). It is believed that ventricular late potentials when detected after day 5 after MI are relatively stable and carry the most significant relation to subsequent arrhythmic events. This study sought to determine if ventricular late potentials in patients after MI exhibit variability when recordings were made 10 to 12 hours apart on day 7 and to assess the clinical significance of this variability.

Abdominal Tuberculosis or Ovarian Carcinoma: Management Dilemma Associated With an Elevated CA-125 Level.

The CA-125 antigen is useful for detecting residual disease in women treated for ovarian cancer. Its role in screening for ovarian cancer is questionable, however, because anumber of other benign and malignant causes can elevate its level. In this case, a patient with genital tract tuberculosis was initially misdiagnosed with ovarian cancer.