[The enzymatic activity of the neurosecretory nuclei of the anterior hypothalamus in exposure of the body to organophosphorus compounds].

Under study were activities of glycolysis enzymes: LDH, Krebs' cycle--SDH, those of electron transport system--NAD and NADP-diaphorase, and of the hydrolytic enzymes, acid and alkaline phosphatases in the hypothalamus, as were morphofunctional shifts in these enzymes' activities in poisoning with organophosphorus compounds. The experiments were carried out in 72 white male outbred rats weighing 180-200 g, that were administered PHOS antio (an organo-phosphorus compound) in a daily dose of 0.1 LD50 for 30 days.

[The neuroendocrine system and specific factors of immunity in pesticide poisoning].

Experiments performed effects of chronic administration of organophosphate pesticide "Antio" (dose 1/100 LD50) on specific factors of immunity and corticosterone (CS) levels in the blood. Adult male Wistar rats were used in all experiments. The immunological indexes were increased, CS levels were decreased.