[Characteristics of the cellular reactions of the T- and B-dependent areas of the regional lymph nodes in dogs to the administration of immunodepressants].

Mesenteric, bifurcational, axillary and popliteal lymph nodes have been studied in 22 healthy mature male dogs. Amount of blast cells, small lymphocytes, plasma cells and macrophages has been taken into account in the paracortical zone, in the germinative centers and in the medullary cords. For two weeks to one group of the animals every day imuran in turn with aurantin (10 mg/kg and 25 mg/kg) are injected, or antilymphocytic serum (ALS) intraperitoneally every other day (0.

[Current immunological aspects of infectious diseases].

The author discusses different variants of a possible interaction between the infectious agent and the immunological system of the human organism. It was shown that the same causative agent could induce various clinical manifestations of the disease, depending on the functional condition of the immunocompetent system, particularly of the T-lymphoid system. The author believes that in connection with this, proper methods of treatment of infectious diseases (with consideration to the state of the functional activity of the organism's immunological system) could promote successful specific prophylaxis and therapy.

[The quantity of immunoglobulins (A, G, M) in different forms of typhoid fever].

Results of determination of the quantitative content of immunoglobulins (IgA, IgG and IgM) demonstrated chronic typhoid carrier state to be a dynamic process characterized by high IgA and IgG indices which began to form as early as the acute period. A complex of clinico-laboratory indices permitted to detect the latent phase of the carrier state among the persons who sustained typhoid fever within the range of 30%; this confirmed the statement of a number of investigators put forward earlier that the true number of carriers was much greater than that recorded.

[Quantitative determination of specific immunoglobulins in the serum of bacterial carriers of abdominal typhus].

As a result of determination of immunoglobulins of class A and M by the method of simple radial immunodiffusion with the use of monospecific antiglobulin sera it appeared that in the sera of carriers immunogolubins M were contained in much lesser quantity than in typhoid patients. The content of immunoglobulins A was somewhat greater in the blood sera of carriers.