Comparison of Morphological and Histological Characteristics of Human and Sheep: Sheep as a Potential Model for Testing Midurethral Slings in vivo.

Introduction: The sheep was evaluated as a potential model for preclinical evaluation of urethral slings in vivo based on: (1) anatomical measurements of the sheep vagina and (2) histological tissue integration and host response to polypropylene (PP) slings.

Methods: Eight female, multiparous sheep were utilized. Three of 8 animals underwent surgery mimicking human tension-free vaginal tape protocols for midurethral slings and were euthanized at 6 months.

Prevalence of myocardial perfusion scintigraphy derived ischemia in coronary lesions with discordant fractional flow reserve and non-hyperemic pressure ratios.

Background: Whether a coronary lesion with discordant fractional flow reserve (FFR) and non-hyperemic pressure ratios (NHPRs) causes myocardial ischemia remains unclear. This study investigates the prevalence of myocardial ischemia as assessed by myocardial perfusion scintigraphy (MPS) in coronary lesions with discordant FFR and instantaneous wave-free ratio (iFR), and, additionally, other NHPRs: resting full-cycle ratio (RFR), diastolic pressure ratio (dPR), and resting Pd/Pa.

Methods: A total of 484 coronary arteries in 295 patients with stable coronary artery disease that underwent MPS and invasive physiological pressure measurements were categorized into four groups (FFR+/NHPR+, FFR+/NHPR-, FFR-/NHPR+, and FFR-/NHPR-) using the respective cut-off values of FFR ≤ 0.

Cluster-Based Analysis of Retinitis Pigmentosa Modifiers Using Eye Size and Gene Expression Data.

The goal of this research is to computationally identify candidate modifiers for retinitis pigmentosa (RP), a group of rare genetic disorders that trigger the cellular degeneration of retinal tissue. RP being subject to phenotypic variation complicates diagnosis and treatment of the disease. In a previous study, modifiers of RP were identified by an association between genetic variation in the DNA sequence and variation in eye size in a well-characterized model of RP.

CHRIST: CD44-Incorporated Hepatocellular Carcinoma Risk Index Scoring Tool-A Novel Prognostic Scoring System for Hepatocellular Carcinoma Development and Aggressiveness.

CD44 has been demonstrated to play a pivotal role in regulating tumor cell progression, including hepatocellular carcinoma (HCC) development. Here, we aimed to establish a scoring system to evaluate the risk of developing HCC utilizing CD44-rs187115 SNP polymorphism. A prospective cohort of 120 individuals was enrolled in four groups: 19 non-metastatic HCC patients, 21 metastatic, 40 patients with hepatitis C-related cirrhosis, and 40 controls.

Robot System Assistant (RoSA): Towards Intuitive Multi-Modal and Multi-Device Human-Robot Interaction.

This paper presents an implementation of RoSA, a Robot System Assistant, for safe and intuitive human-machine interaction. The interaction modalities were chosen and previously reviewed using a Wizard of Oz study emphasizing a strong propensity for speech and pointing gestures. Based on these findings, we design and implement a new multi-modal system for contactless human-machine interaction based on speech, facial, and gesture recognition.

Single stage open reduction, intramedullary rod, bone grafting, and plate fixation for managing adolescent midshaft femoral fracture non-union, report of two cases.

Although rare, long bones fracture non-union in pediatric and adolescent patients is still being reported. It poses a challenge for the trauma surgeons, although principles for adult patient management apply to pediatrics and adolescents; however, there is no standard protocol to deal with such situations. We report two male adolescent patients, 11 and 12 years old, presented with non-united midshaft femoral fracture non-union after being multiply operated on.

Offloading Plantar Pressures in Healthy Adults: Stirrup Cast vs Total Contact Cast.

Background: Diabetic foot ulcers are associated with significant morbidity and mortality while posing a challenge for healthcare professionals. Offloading is considered the mainstay of treatment. Total contact casting (TCC) is widely used but does not effectively offload the hindfoot.

Knockdown of confers strigolactones mediated rhizobia interaction and promotes nodulation in soybean.

Background: Strigolactones (SLs) play a key role in modulating plant root growth, shoot branching, and plant-symbiont interaction. However, despite their significance, the components of SL biosynthesis and signaling in soybean and their role in soybean-rhizobia interaction is unknown.

Methods: In this study, we identified and functionally characterized the from soybean.

Perceptions of Clinical Dental Students Toward Online Education During the COVID-19 Crisis: An Egyptian Multicenter Cross-Sectional Survey.

To evaluate the perceptions of clinical dental students on the role of online education in providing dental education during the COVID-19 crisis. A cross-sectional online survey was sent to four Egyptian dental schools from the 20th of January 2021 to the 3rd of February 2021. Survey questions included the demographics, uses, experiences, perceived benefits, and barriers of distance learning in dentistry during the COVID-19 pandemic.

Management of anterior associated types of acetabular fractures utilizing the modified Stoppa and the pararectus approaches: a prospective cohort study and early experience from a level one Egyptian trauma centre.

Purpose: This study aimed to report the early experience (radiographic, functional, and complications outcomes) from an Egyptian (North African) level one trauma centre after utilizing the modified Stoppa and the pararectus approaches to manage anterior-associated types of acetabular fractures.

Patients And Methods: Between January 2014 and April 2018, 63 patients (40 males and 23 females) with a mean age of 33 ± 11.5 were included, 45 patients were treated through the modified Stoppa (group A), and 18 through the pararectus approach (group B).

Scaling the Children Immunization App (CIMA) to Support Child Refugees and Parents in the Time of the COVID-19 Pandemic: A Social Capital Approach to Scale a Smartphone Application in Zaatari Camp, Jordan.

Background: Children vaccination is a key intervention for their survival, especially among refugees. Yet, children vaccination registration is done manually in refugees camps and there is no possibility to send reminders to parents to come back on time. We aimed to boost the parental registration of children's vaccination records on a Children Immunization app (CIMA) while also availing the parents with useful parenting skills under COVID-19-related stress.

Vibration, acoustic and emission characteristics of the chlorella vulgaris microalgae oil in compression ignition engine to mitigate environmental pollution.

The petroleum fuel demand with high price and its exhaustion imposes a pressure to find an alternative. The fossil fuel shortage has been deteriorating over the past few years, because of the rapid increase in population. Many attempts have been made to increase the quality of biofuel with additives.

Assessment of Glutathione Peroxidase-1 (GPX1) Gene Expression as a Specific Diagnostic and Prognostic Biomarker in Malignant Pleural Mesothelioma.

Malignant pleural mesothelioma (MPM) is a malignant tumor of the mesothelial lining of the thorax. It has been related to frequent exposure to asbestos. Diagnosis of malignant pleural mesothelioma is considered a criticizing problem for clinicians.

Awareness and perception of COVID-19 among final-year dental students, Sudan.

Background: Infection with COVID-19 has serious consequences, which may lead to severe pneumonia and even death. There is a high risk of infection between dental personnel and patients due to working in proximity while performing dental treatments.

Objective: This study aims to assess the awareness about COVID-19 and its preventive measures among final-year dental students.

Magnetoelectric (ME) Antenna for On-chip Implantable Energy Harvesting.

A novel magnetoelectric (ME) antenna is fabricated to be integrated to the on-chip energy harvesting circuit for brain-computer interface applications. The proposed ME antenna resonates at the frequency of 2.57 GHz while providing a bandwidth of 3.

Potential value of pharmacological agents acting on toll-like receptor (TLR) 7 and/or TLR8 in COVID-19.

The COVID-19 pandemic is an ongoing global pandemic of coronavirus disease 2019 as an atypical type of viral pneumonia caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Many potential pharmacotherapies are currently being investigated against this disease. This article points to and justifies, the importance of investigating the potential therapeutic value of pharmacological agents acting on Toll-like Receptor (TLR) 7 and/or TLR8 as double-edged swords combating COVID-19.

Comparison of cracking activity of the core-shell composite MCM-41/HY & MCM-48/HY catalysts in the synthesis of organic liquid fuel from Mahua oil.

A synergistic catalyst was architectured using the hydrothermal crystallization method. Mesoporous material with pore diameter less than 20 nm was grown on the microporous Zeolite HY. The catalysts were characterized by XRD, ICP-OES, BET, TPD, SEM and TEM techniques.

The Windlass Tourniquet: Is It Taking the Wind Out of the "Stop the Bleed" Sails?

Background: Civilians are often first-line responders in hemorrhage control; however, windlass tourniquets are not intuitive. Untrained users reading enclosed instructions failed in 38.2% of tourniquet applications.

Acute Correction and Plate Fixation for the Management of Severe Infantile Blount's Disease: Short-term Results.

Purpose: The purpose of this study is to evaluate the short-term results of lateral closing wedge osteotomy with medial hemiplateau elevation for the management of severe infantile Blount's disease.

Materials And Methods: In this prospective study, 11 cases of severe Blount's disease (Langenskiold stages five and six) were managed in the period between January 2017 and January 2020. Double osteotomy technique was applied, namely a metaphyseal closing wedge and a medial hemiplateau elevation, through a single midline incision.

The development of microfabricated solenoids with magnetic cores for micromagnetic neural stimulation.

Electrical stimulation via invasive microelectrodes is commonly used to treat a wide range of neurological and psychiatric conditions. Despite its remarkable success, the stimulation performance is not sustainable since the electrodes become encapsulated by gliosis due to foreign body reactions. Magnetic stimulation overcomes these limitations by eliminating the need for a metal-electrode contact.

Impact of Maternal Body Mass Index on Maternal and Neonatal Outcomes Among Sudanese Women.

Background: Unhealthy weight has an adverse impact on a person's general health, this is more serious for pregnant a woman as it can affect her baby as well. Nutrition is an important element of antenatal care. Nutrition must be optimum to avoid problems of being underweight, and that of overweight.