Determining the Impact of the Reversal of Roe v. Wade on Birth Control and Infertility Trends Using Google Trends.

Introduction Overturning Roe v. Wade left many concerned about birth control options and future fertility. This study aims to report Google (Google, Inc.

Delayed Morbidity Associated With Surgical Management of Urosymphyseal Fistula.

Objective: To characterize and identify factors associated with long-term morbidity of definitive urosymphyseal fistula (USF) treatment.

Methods: Retrospective chart review of a single institution database identified 57 patients who underwent operative treatment of USF between 2009 and 2022 with at least 90 days of follow-up. Delayed complications were considered those occurring ≥90 days following surgery.

Initial Experience and Clinical Assessment of the Karl Storz FLEX-XC1 Single-Use Flexible Ureteroscope.

Introduction: The Karl Storz FLEX-XC1 is a novel single-use flexible ureteroscope that uses the same videographics platform as its reusable digital counterpart. We evaluated the technical performance of the FLEX-XC1 in its initial clinical use.

Methods: We reviewed a series of consecutive ureteroscopy procedures performed by 2 endourologists using the FLEX-XC1 for indications for which we typically use a single-use device: total stone burden > 15 mm or > 10 mm in the lower pole, anticipated case duration > 60 minutes, bilateral procedure, or upper tract urothelial cancer procedures.

Sacral insufficiency fractures are a frequent and painful consequence of pubic symphysis osteomyelitis.

Background: Pubic symphysis osteomyelitis can result from urosymphyseal fistula formation. High rates of sacropelvic insufficiency fractures have been reported in this population. The aim of this study was to describe the presentation and risk factors for sacral insufficiency fractures (SIF) associated with surgical treatment of pubic symphysis osteomyelitis.

Endoscopic Urethroplasty Using Buccal Graft for Male Membranous Urethral Stricture.

Objective: To demonstrate a new minimally invasive endoscopic approach to urethroplasty.

Methods: The procedure was performed in a male patient with prior history of prostate cancer managed by radiation who subsequently developed an 8 mm flow-limiting membranous urethral stricture. After stricture dilation a 1 cm wide strip of superficial mucosa was resected from the bladder neck past the area of stricture, creating a bed for the graft to lay.

Addressing the need for more therapeutic options in neuroendocrine prostate cancer.

Introduction: Neuroendocrine prostate cancer (NEPC) is an aggressive form of prostate cancer frequently seen after prolonged treatment of castration resistant prostate cancer (CRPC). NEPC has become increasingly prevalent over the last 20 years, with a poor prognosis caused by a late diagnosis and limited treatment options. Recent advances in PET/CT imaging and targeted radioimmunotherapy are promising, but more research into additional treatment options is needed.

Environmental impact of single-use and reusable flexible cystoscopes.

Objectives: To compare the carbon footprint and environmental impact of single-use and reusable flexible cystoscopes.

Materials And Methods: We analysed the expected clinical lifecycle of single-use (Ambu aScope™ 4 Cysto) and reusable (Olympus CYF-V2) flexible cystoscopes, from manufacture to disposal. Performance data on cumulative procedures between repairs and before decommissioning were derived from a high-volume multispecialty practice.

Peripheral chemoreflex modulation of renal hemodynamics and renal tissue PO2 in chronic heart failure with reduced ejection fraction.

Aberrant carotid body chemoreceptor (CBC) function contributes to increased sympathetic nerve activity (SNA) and reduced renal blood flow (RBF) in chronic heart failure (CHF). Intermittent asphyxia (IA) mimicking sleep apnea is associated with additional increases in SNA and may worsen reductions in RBF and renal PO2 (RPO2) in CHF. The combined effects of decreased RBF and RPO2 may contribute to biochemical changes precipitating renal injury.

Genome-resolved metagenomics to study co-occurrence patterns and intraspecific heterogeneity among plant pathogen metapopulations.

Assessment of pathogen diversity in agricultural fields is essential for informing management decisions and the development of resistant plant varieties. However, many population genomic studies have relied on culture-based approaches that do not provide quantitative assessment of pathogen populations at the field-level or the associated host microbiome. Here, we applied whole-genome shotgun sequencing of microbial DNA extracted directly from the washings of pooled leaf samples, collected from individual tomato and pepper fields in Alabama that displayed the classical symptoms of bacterial spot disease caused by Xanthomonas spp.

Independent Evolution with the Gene Flux Originating from Multiple Species Explains Genomic Heterogeneity in Xanthomonas perforans.

is the predominant pathogen responsible for bacterial leaf spot of tomato and for that of pepper in the southeast United States. Previous studies have indicated significant changes in the population collected from Florida tomato fields over the span of 2 decades, including a shift in race and diversification into three phylogenetic groups driven by genome-wide homologous-recombination events derived from In our sampling of strains associated with bacterial spot disease in Alabama, we were readily able to isolate from symptomatic pepper plants grown in several Alabama counties, indicating a recent shift in the host range of the pathogen. To investigate the diversity of these pepper-pathogenic strains and their relation to populations associated with tomatoes grown in the southeast United States, we sequenced the genomes of eight strains isolated from tomatoes and peppers grown in Alabama and compared them with previously published genome data available from GenBank.

A Multivirus Epidemic of Tomatoes in Alabama.

During 1992, a multivirus epidemic reduced tomato production by as much as 25% in the major tomato-growing region of Alabama. Estimated yield losses of 100% resulted from the epidemic in over 250 ha in two counties of North Alabama. Cucumber mosaic cucumovirus (CMV), alone or in combination with potato potyvirus Y (PVY) and/or tobacco etch potyvirus (TEV), was responsible for the crop failure.

Man's hand in evolution.

In developmental terms, the human hand is at the same time both specialised and primitive. Its manipulative ability, though somewhat better than that of the apes and monkeys, has lost strength compared with hands of recently extinct species of Man, and shows some evolutionary characteristics seen in reptiles of 250 million years ago. Its evolution, as presently understood, is described.

A clinical evaluation of the air-fluidised bed in a general plastic surgery unit.

Over a period of seven months nine patients were nursed on an air-fluidised bed. Measurements showed that skin-bed interface pressures were significantly lower on this bed than on a conventional hospital bed, particularly over the areas of the highest pressure. Whilst the bed did not shorten the patients' hospital stay, it did simplify nursing and improve patient comfort, especially in burns cases.

Functional disability in the rheumatoid hand.

The investigation of sixty-one rheumatoid patients relates their hand function to measured hand deformity. Certain deformities are related to a reduction in function; others are not. The dominant hand, used more frequently, deteriorates more quickly than the non-dominant.

Scanning electronmicroscopy of hypertrophic and keloid scar.

The scanning electronmicroscopic appearances of hypertrophic and keloid scar before and after treatment, mature scar and normal skin have been investigated. There is a graduation of features such as collagen orientation and fibre size which accompanies the clinical maturation from the active hypertrophic state into mature scar, a process which is hastened but not materially altered by treatment with steroid or compression-occlusion.

Enzyme activity in human scars, hypertrophic scars and keloids.

Biopsies from non-hypertrophic and hypertrophic scars and from normal skin have been studied histochemically for activities of nicotanamide adenine dinucleotide diaphorase, lactate dehydrogenase, acid phosphatase, beta-D glucuronidase and alkaline phosphatase. The activities of all enzymes studied except alkaline phosphatase were found to be increased in hypertrophic scars as compared with non-hypertrophic scars and normal skin.