[ECOLOGICAL AND GEOGRAPHIC ANALYSIS OF THE SPREAD OF MITES OF THE FAMILY TROMBICULIDAE IN MONGOLIA].

The paper gives data on the fauna of chigger mites (Thrombiculinae), the ectoparasites of small mammals in Mongolia. The ecological and geographic analysis could reveal the major abiotic and biotic determinants of the spread of the chigger mites and make a map of their potential area.

Highly pathogenic influenza H5N1 virus of clade 2.3.2.1c in Western Siberia.

In the spring of 2015, avian influenza virus surveillance in Western Siberia resulted in isolation of several influenza H5N1 virus strains. The strains were isolated from several wild bird species. Investigation of biological features of those strains demonstrated their high pathogenicity for mammals.

[Molecular-biological characteristic of Yersinia enterocolitica circulating in various regions of Russian Federation].

Aim: Complex characteristic by phenotype signs and main virulence genes of Yersinia enterocolitica strains circulating in various regions of Russian Federation.

Materials And Methods: 46 strains of Y. enterocolitica of 2 - 4 biotypes and 401 strains of Y.

[Detection of RNA and specific antibodies against influenza virus A (H5N1) in human samples].

Results of inspection 451 persons in the age of from 19 till 58 years and 2 children in the age of till 2 years on presence of specific antibodies and RNA of the infuenza virus A (H5N1) are submitted. RNA of infuenza virus A (H5N1) in researched samples is not revealed. Specific antibodies to a infuenza virus A (H5N1) in a blood serum of 211 patients and donors it is not revealed.

[Antiviral activity of oral ultralow doses of antibodies to gamma-interferon: experimental study of influenza infection in mice].

Course intragastric administration of ultralow doses of human gamma-interferon antibodies (ULD anti-IFN-gamma) to intact mice resulted in an increase of endogenous IFN-gamma production by the animal lymphocytes. Oral prophylactic administration of ULD anti-IFN-gamma significantly lowered the influenza virus concentration in the animal lungs at the initial stage of the aerogenous infection: in 2 (p = 0.05) and 3 (p = 0.

[Biologically active substances during treatment of pulmonary hypertension with ATP infusions immediately after general anesthesia and surgery of hypervolemic congenital heart defects].

In 95 patients with hypervolemic congenital heart valve defects (42 with interventricular and interatrial septal defects, and 53 with patent ductus arteriosus) mixed venous blood levels of serotonin, histamine, adrenalin, noradrenaline, total 11-hydroxycorticosteroids were studied using spectrofluorimetry, cyclic adenosine- and guanosine monophosphate (cAMP and cGMP), prostaglandins E + A and F2 alpha and their interaction were assessed using radioimmunoassay and correlation analysis, respectively. Immediately after general anesthesia and surgical correction of septal defects using cardiopulmonary bypass adrenalin level was increased, while noradrenaline, cAMP, cGMP, prostaglandin E + A levels remained high. Similar pattern was observed in patients after arterial duct ligation.

[Biologically active substances in patients with hypervolemic congenital heart defects undergoing general multicomponent anesthesia].

In 95 patients with hypervolemic congenital heart diseases (42 with interventricular and interatrial septal defects, and 53 with patent ductus arteriosus) mixed venous blood levels of serotonin, histamine, adrenalin, noradrenaline, total 11-hydroxycorticosteroids were studied using spectrofluorimetry, cyclic adenosine- and guanosine-monophosphate (cAMP and cGMP), prostaglandins E+A and F2 alpha and their interaction were assessed using radioimmunoassay and correlation analysis, respectively. Before surgical treatment the patients showed higher (than in the control) concentrations of histamine, adrenalin, noradrenaline, cAMP, and cGMP, prostaglandins E+A. During anesthesia including fentanyl, morphine, diazepam, N2O:O2 in patients with heart valve defects cGMP level was increased and in patients with patent ductus arteriosus cAMP level was increased during analogous anesthesia with morphine replaced by halothane.

[Treatment of pulmonary hypertension in the immediate period after general anesthesia and surgical correction of patent ductus arteriosus and heart septal defects].

Surgical correction of the arterial duct and defects of the cardiac septa is followed in the nearest period after surgical correction by lung hypertension which considerably aggravates the postoperative period. The observation of 74 patients has shown that infusions of 1% solution of phosphobion (0.05 mg/kg/min) in the pulmonary artery decrease the pressure in the pulmonary artery, pulmonary-vascular resistance, make the incidence of disturbed heart rate less frequent, reduce the concentration of noradrenaline and prostaglandins.

[Vasoactive hormone metabolism in the lungs of patients with congenital heart defects].

The role of pulmonary metabolism of adrenaline, noradrenaline (NA), serotonin and histamine in the pathogenesis of hemodynamic disorders was examined in relation to the magnitude of intracardiac discharge (ID) in 30 patients with septal defects. Irrespective of the magnitude of arteriovenous ID, pulmonary tissue deactivation of NA is shown to be disrupted. Where ID averages 7.