Publications by authors named "K van de Kamp"
Background: Whether pathophysiological factors differ between males and females with irritable bowel syndrome-diarrhea (IBS-D) remains to be tested. To better understand potential sex differences, males with IBS-D were compared to naturally cycling females and to females with IBS-D taking hormonal contraception on plasma levels of cytokines and gut microbiome characteristics.
Methods: Males and females with Rome III IBS-D completed questionnaires and kept a daily symptom diary for 28 days.
Background: Medically refractory Crohn's disease (CD) is associated with a high risk of complications. Mycophenolate mofetil (MMF), a small molecule immunosuppressant, has limited data in patients with CD, and objective endoscopic response to MMF has not been reported.
Aims: We evaluated the safety and clinical, endoscopic, and biochemical effectiveness of off-label MMF for refractory CD as monotherapy or in combination with a biologic in patients with CD.
Background: This study aimed to describe the patient-reported factors that impact sleep among individuals with inflammatory bowel disease (IBD), aligning with the Social Ecological Model of Sleep. This addresses the gap in IBD sleep research, which predominantly focuses on individual-level factors and their impact on sleep.
Methods: Adults (ages 18-65) with IBD were recruited online through ResearchMatch in June 2023.
Background And Aims: Individuals with inflammatory bowel disease (IBD) experience a high symptom burden, including abdominal pain, fatigue, anxiety, depression, and sleep disturbances; yet, little is known regarding the relationship between sex and gender on symptoms. We sought to report symptom severity for cisgender men, cisgender women, and transgender and gender-diverse (TGD) individuals. In addition, we used network analysis to identify core symptoms and explore if symptoms and their relationships differ between cisgender men and cisgender women.
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- - The study aimed to understand how heart rate variability (HRV) in the high frequency (HF) range relates to EEG delta band power in women with irritable bowel syndrome (IBS) compared to healthy women.
- - Results indicated that women with IBS experienced more NREM sleep and differing HRV patterns (higher HF, lower low frequency (LF), and a decreased LF/HF ratio), but showed lower delta band power in their EEG readings.
- - The findings suggested a disrupted relationship between the heart and brain activity in IBS patients, indicated by longer lag times between cardiac signals and EEG delta power, although it remains unclear if this dysregulation affects the development of IBS.