Unveiling the Longitudinal Journey: 3-Year Follow-up of Women with MINOCA and INOCA in a Specialized Heart Centre.

Background: Myocardial infarction with no obstructive coronary arteries (MINOCA), and ischemia with no obstructive coronary arteries (INOCA), are female-predominant conditions; clinical trials are lacking to guide medical management for the common underlying vasomotor etiologies. Data on long-term outcomes of (M)INOCA patients following attendance at a women's heart centre (WHC) are lacking.

Methods: Women diagnosed with MINOCA (n = 51) or INOCA (n = 112) were prospectively followed for 3 years at the Leslie Diamond WHC (LDWHC) in Vancouver.

A case of polyploid utility in biocontrol: reproductively-impaired triploid Nasonia vitripennis have high host-killing ability.

Background: Intentionally impairing the fecundity of mass-reared insects has important utility in controlling pest species. Typically, sterilized individuals are competed against wild counterparts, reducing pest population size. A novel consideration is creating biocontrol agents with lower reproductive capacity that are less likely to establish permanently or admix with wild populations, which are both emerging as legal barriers.

Nanomaterial-based synergistic strategies for combating dental caries: progress and perspectives.

Dental caries, as the predominant global oral disease, remains a critical public health issue worldwide, particularly in socioeconomically disadvantaged communities. However, common caries prevention approaches (, oral health education, mechanical plaque removal, and delivery of fluoride agents) are still insufficient for optimal caries management, and therefore, alternative regimens that can supplement existing strategies are highly warranted. Nanomaterials exhibit considerable potential in combating cariogenic pathogens and biofilms owing to their promising antimicrobial capacity, improved penetration into biofilms, targeted precision delivery, and versatile physicochemical properties.