Publications by authors named "K Zwicker"

Article Synopsis
  • PTEN hamartoma tumor syndrome (PHTS) is a rare condition that increases the risk of tumors and is linked to vascular anomalies.
  • A study reviewed seven children with PHTS treated with sirolimus, an mTOR inhibitor, with a median age of 10 years at treatment initiation.
  • After 2.5 years, 86% of patients showed significant improvement, with only minor side effects like mild buccal ulcers and acne, suggesting sirolimus is a safe and effective treatment for vascular issues in PHTS.
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Background: Throughout the COVID-19 pandemic there has been a documented decline in reports to child protective services, despite an increased incidence of child maltreatment. This is concerning for increasing missed cases. This study aims to examine if and how Canadian paediatricians are identifying maltreatment in virtual medical appointments.

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To retrospectively correlate imaging findings post-sclerotherapy of low-flow vascular malformations with clinical outcome. We retrospectively evaluated 81 pediatric patients who had sclerotherapy in our department over a 14-year period. Patients with a diagnosis of low-flow vascular malformation, pre and post-treatment ultrasound (US) and clinical follow-up evaluation were included in the study.

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Les anomalies vasculaires sont des affections hétérogènes qui touchent les vaisseaux sanguins ou lymphatiques. Les enfants atteints peuvent éprouver de la douleur ou une perte fonctionnelle, présenter une infection ou une coagulopathie ou être confrontés à des difficultés psychologiques. Le diagnostic et la prise en charge exigent souvent une approche interdisciplinaire.

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Vascular anomalies are heterogeneous conditions that affect blood and/or lymphatic vessels. Affected children may experience pain, functional loss, infection, coagulopathies, and psychological challenges. Diagnosis and management often warrant an interdisciplinary approach.

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