Publications by authors named "K Ziser"

Article Synopsis
  • - The study investigates the clinical characteristics and incidence of hypersensitivity reactions to sugammadex in Australia, with a focus on cases identified through skin testing at six allergy clinics.
  • - Out of 30 cases analyzed, symptoms primarily included hypotension and flushing, with the median recognition time for reactions being 5 minutes post-administration; life-threatening and non-life-threatening cases showed distinct patterns in tryptase positivity.
  • - The estimated incidence of sugammadex hypersensitivity was found to be 0.004%, which is lower than previous reports, indicating that while these reactions can occur, they are relatively rare.
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Article Synopsis
  • Randomized controlled trials (RCTs) indicate that using sodium glucose cotransporter-2 inhibitors reduces rates of acute kidney injury and renal failure, but observational studies show mixed results, especially for at-risk populations.
  • The research specifically focused on three high-risk groups: older adults over 65, individuals with heart failure, and those with impaired kidney function.
  • Of the 922 studies reviewed, eight met the criteria, revealing that older adults, people with heart failure, and those with reduced kidney function experience a higher absolute risk of acute kidney issues when using these medications, but more evidence is needed to compare the risks across these different groups.
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Background: We investigated the association between post-hospital discharge use of sodium glucose cotransporter-2 inhibitors (SGLT-2is) compared to dipeptidyl peptidase-4 inhibitors (DPP-4is) and the incidence of hospitalization for acute renal failure (ARF) and chronic kidney disease (CKD) in people with type 2 diabetes.

Methods: We conducted a retrospective cohort study using linked hospital and prescription data. Our cohort included people aged ≥30 years with type 2 diabetes discharged from a hospital in Victoria, Australia, from December 2013 to June 2018.

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Background: Childhood and adolescent overweight and obesity are among the most serious health challenges today. Structured weight reduction programs can be helpful to reduce severe health consequences but evidence is partly scarce. The STARKIDS program aims to improve on some of these limitations and is designed to be a structured, stepwise, digitally supported intervention program for the whole family.

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Objective: Predictors of body weight loss (BWL) and body weight loss maintenance (BWLM) after behavioral weight loss intervention are well-investigated in adults. Less is known for children and adolescents and a systematic overview on the topic for this age group was aim of the review.

Methods: A systematic research according to PRISMA guidelines using several databases was performed.

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