Publications by authors named "K Zahedi"
Article Synopsis
- Erosive genital lichen planus (EGLP) is a painful condition causing significant discomfort and complications in the genital area, highlighting the need for comprehensive care and effective treatment strategies.
- A systematic review of 26 studies on EGLP treatments was conducted, focusing on the effectiveness of various therapies, including topical corticosteroids and emerging treatments.
- The management of EGLP should be personalized, combining different treatment methods while prioritizing the patient's overall well-being and addressing both physical and emotional challenges.
Article Synopsis
- Tuberous sclerosis complex (TSC) is linked to kidney issues, specifically renal cysts and benign tumors, which can lead to kidney failure.
- Research shows inactivation of carbonic anhydrase 2 reduces cyst formation, while deletion of the Foxi1 gene nearly eliminates cysts in knockout mice.
- By 110 days, knockout mice showed significant cyst development, correlating with increased Foxi1 expression and mTORC1 activation, unlike double-knockout mice (dKO) that had no cysts at either 47 or 110 days.
Cisplatin, a chemotherapeutic agent, can cause nephrotoxic and ototoxic injuries. Using a mouse model of repeated low dose cisplatin (RLDC), we compared the kidneys of cisplatin- and vehicle-treated mice on days 3 (early injury phase) and 35 (late injury/recovery phase) after the final treatment. RNA-seq analyses revealed increases in the expression of markers of kidney injury (e.
View Article and Find Full Text PDFTinea capitis is a common dermatophyte infection of the scalp in children. It is an uncommon infection in adults and usually affects postmenopausal women and immunocompromised patients. We report an immunocompetent elderly female with inflammatory tinea capitis caused by and review the literature for the past 5 years to describe the disease, its epidemiologic characteristics, dermatophyte species involved and treatment options used.
View Article and Find Full Text PDFSystemic lupus erythematosus (SLE) is a systemic autoimmune disease that affects several organs including the skin. Clinical cutaneous symptoms of SLE come in a broad range, consisting of both non-specific and specific cutaneous lesions. Except for cases of amicrobial pustulosis of the folds, generalized pustular psoriasis, acneiform eruptions, pustular vasculitis, Wells' syndrome, subcorneal pustular dermatosis, and neutrophilic dermatosis, there are no reports of pustular lesions linked to SLE.
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