Publications by authors named "K Yu Kolosova"
Aim To compare efficacy and safety of treatments with the calcium antagonist (CA) verapamil, the cardioselective β-blocker (BB) bisoprolol, and a combination therapy with bisoprolol and amlodipine in patients with stable angina (SA) with concurrent mild and moderate, persistent bronchial asthma (BA). Material and methods This open, prospective, randomized, comparative study included 120 patients with an IHD+BA comorbidity. Of these patients, 60 had mild persistent BA and 60 had moderate persistent BA.
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- This study aimed to assess the effectiveness of immediate injection treatments (dexamethasone, hyaluronic acid/gelatin hydrogel, and glycol-chitosan) on the vocal function of rabbits after a surgical injury to their vocal folds.
- Twelve rabbits underwent a vocal fold injury and were divided into groups receiving different treatments, including a control group that received saline.
- Results indicated that dexamethasone led to a lower fundamental frequency in vocal folds compared to the saline group, suggesting it may help reduce scarring, but further research is needed to confirm these findings.
Objectives/hypothesis: In animal studies of vocal fold scarring and treatment, imaging-based evaluation is most often conducted by tissue slicing and histological staining. Given variation in anatomy, injury type, severity, and sacrifice timepoints, planar histological sections provide limited spatiotemporal details of tissue repair. Three-dimensional (3D) virtual histology may provide additional contextual spatial information, enhancing objective interpretation.
View Article and Find Full Text PDFAim To study the antianginal and heart rate slowing effects in patients with stable angina (SA) who failed to achieve the heart rate (HR) goal and were switched from the beta-blocker (BB) metoprolol tartrate to a combination of metoprolol tartrate and ivabradine.Materials and methods The study included 54 patients with SA not higher than functional class (FC) III (35 (64.8 %) men and 19 (35.
View Article and Find Full Text PDFAim: To study the whole range of esophageal disorders in patients with irritable bowel syndrome (IBS) using high-tech methods.
Materials And Methods: 102 IBS patients (47 males, mean age 40.8, diagnosis of IBS was established according to Rome III criteria) with esophageal symptoms (heartburn, belching, globus sensation and noncardiac chest pain) were examined in gastroenterology department.