Role of mast cell in locally advanced rectal cancer treated with neoadjuvant chemoradiotherapy.

The pro-tumor effects of mast cell (MC) in the tumor microenvironment (TME) are becoming increasingly clear. Recently, MC were shown to contribute to tumor malignancy by supporting the migration of tumor-associated macrophages (TAMs), suggesting a relationship with tumor immunity. In the current study, we aimed to examine the correlation between MC infiltration and neoadjuvant chemoradiotherapy (nCRT) response for locally advanced rectal cancer (LARC).

Construct validity, responsiveness, and interpretability of the Spinal Cord Injury Functional Ambulation Inventory (SCI-FAI).

Objective: We investigated the construct validity, responsiveness, and interpretability of the Spinal Cord Injury Functional Ambulation Inventory (SCI-FAI) to determine its usefulness in measuring the functional level of gait.

Patients And Methods: This was a prospective observational study following the checklist of the Consensus-Based Standards for Selecting Health Measurement Instruments. The SCI-FAI consists of three items: Gait Parameter, Assistive Devices, and Temporal.

Carbon dioxide insufflation to facilitate epicardial access in ECMO-supported ventricular tachycardia ablation.

Carbon dioxide injection through coronary vein puncture can greatly reduce complications from epicardial access. We reported a case of ventricular tachycardia that was successfully ablated by this procedure under ECMO support.

Benefits of Continuous Outpatient Orthopedic Consultations for Both Upper and Lower Body on the Mortality Rates of Hemodialysis Patients.

Background: The purpose of the present observational study was to examine whether there is a difference in prognosis for hemodialysis patients with or without continued orthopedic outpatient visits over five years.  Methods: One hundred and thirteen hemodialysis patients who visited the dialysis center of Takagi Hospital, Okawa, Japan, as of December 2017 were included in this study. Data were collected from the medical records until December 2022.

Pilot Study on the Relationship Between Different Lower Limb Raising Velocities and Trunk Muscle Contraction in Active Straight Leg Raise.

Background/objectives: The active straight leg raise requires intricate coordination between the hip, knee, pelvis, and spine. Despite its complexity, limited research has explored the relationship between lower limb raising velocity and trunk muscle motor control during an active straight leg raise in healthy individuals. This study aimed to explore the potential effects of increased lower limb raising velocity on core muscle contractions during active straight leg raises.