Impact of Changes in Psoas Muscle Index on Prognosis in Patients With Colorectal Liver Metastases.

Background/aim: Reduction in skeletal muscle mass during chemotherapy is associated with poor outcomes. This study investigated the impact of changes in the psoas muscle index (PMI) on the prognosis of patients with unresectable colorectal liver metastases (CRLM) undergoing chemotherapy, including subgroup analyses based on the initial treatment response assessment.

Patients And Methods: We evaluated 47 patients with unresectable CRLM who underwent systematic chemotherapy and assessed changes in PMI to determine their prognosis.

The High Prevalence of Orientia tsutsugamushi Among Wild Rodents and the Identification of Its Major Serotypes in Yamaguchi Prefecture, Japan, Where Scrub Typhus Patients Are Rarely Identified.

Orientia tsutsugamushi (OT) is an obligate intracellular bacterium transmitted by larval trombiculid mites, responsible for scrub typhus in humans. In Japan, approximately 500 human cases are reported annually, with six major serotypes identified as Kato, Karp, Gilliam, Irie/Kawasaki, Shimokoshi, and Hirano/Kuroki. However, the prevalence of OT in Yamaguchi prefecture remains largely unknown.

Geographical Variation of Antimicrobial Resistance of in Japanese Chicken.

Chicken is a potent source of infection in humans. Occasionally, patients with severe enteritis require antimicrobial therapy. Antimicrobials are used to prevent and treat bacterial infections in broiler and breeder farms.