Publications by authors named "K Yildirim"
Total resection of glioblastoma (GB) tumors is nearly impossible, and systemic administration of temozolomide (TMZ) is often inadequate. This study presents a hybrid layered composite nanofiber mesh (LHN) designed for localized treatment in GB tumor bed. The LHN, consisting of polyvinyl alcohol and core-shell polylactic acid layers, was loaded with TMZ and rutin.
View Article and Find Full Text PDFArticle Synopsis
- - The EyeMatics project is part of Germany's Medical Informatics Initiative, focusing on improving treatment for eye diseases through better understanding of intravitreal injection effects.
- - It aims to enhance patient data integration and visualization from various hospital systems, while promoting strong governance and patient involvement.
- - The project employs AI methods to analyze data and biomarkers, emphasizing user-centered strategies for effective implementation and evaluation in a multi-site observational study.
Single incision laparoscopic surgery for hepatocellular carcinoma.
World J Gastrointest Surg
October 2024
Article Synopsis
- Single incision laparoscopic liver resection (SILLR) is a new technique for liver surgery that has been slower to adopt for treating liver tumors compared to traditional multiport methods.
- A review of existing literature was conducted on SILLR's application specifically for hepatocellular carcinoma (HCC), involving data from 195 patients who underwent this procedure.
- The paper examines the feasibility of SILLR, its perioperative and postoperative outcomes, guidelines for selecting appropriate patients, and whether it adheres to important cancer treatment principles.
The thermoalkaliphile possesses a highly branched respiratory chain. These primarily facilitate growth at a wide range of dissolved oxygen levels. The aim of this study was to investigate the regulation of respiratory chain.
View Article and Find Full Text PDFArticle Synopsis
- Tuberculosis, caused by Mycobacterium tuberculosis, is a significant global health issue, and rising drug resistance highlights the urgent need for new treatments.
- Computer-aided drug design (CADD) is being utilized to create more effective and less toxic drugs for tuberculosis.
- The study focused on two synthetic peptides, AKVUAM-1 and AKVUAM-2, which were designed to block interactions crucial for M. tuberculosis infection, showing promise without harming normal lung tissue and having varied minimum inhibitory concentrations (MIC) against different bacterial strains.