Biologic Augmented Scaffold-based cartilage repair: Addressing Complications and Enhancing Outcomes.

Cartilage repair remains a significant challenge due to the tissue's limited innate regenerative capacity. Despite advances in techniques such as microfracture, autologous chondrocyte implantation (ACI), and osteochondral grafting, long-term outcomes are often compromised by complications, including suboptimal tissue integration, graft resorption, and mechanical instability. Recently, biologically augmented scaffold-based cartilage repair has emerged as a promising approach for full-thickness osteochondral lesions.

Characterization of Factors Associated With Death in Deceased Patients With Mitochondrial Disorders: A Multicenter Cross-Sectional Survey.

Background And Objectives: Mitochondrial disorders are multiorgan disorders resulting in significant morbidity and mortality. We aimed to characterize death-associated factors in an international cohort of deceased individuals with mitochondrial disorders.

Methods: This cross-sectional multicenter observational study used data provided by 26 mitochondrial disease centers from 8 countries from January 2022 to March 2023.

Microbe-assisted fabrication of circularly polarized luminescent bacterial cellulosic hybrids.

The fabrications of circularly polarized luminescent (CPL) material are mainly based on the chemical and physical strategies. Controlled biosynthesis of CPL-active materials is beset with difficulties due to the lack of bioactive luminescent precursors and bio-reactors. Enlighted by microbe-assisted asymmetric biosynthesis, herein, we show the in situ bacterial fermentation of Komagataeibacter sucrofermentants to fabricate a series of bacterial cellulosic biofilms with CPL of green, orange, red, and near-infrared colors.

Antimicrobial properties of bimetallic-containing mesoporous bioglass against .

Background/purpose: Various pulp-covering materials offer advantages in regenerative root canal treatment, but each has limitations, highlighting the need for more effective antibacterial strategies for pulp repair and regeneration. Mesoporous bioactive glasses (MBG) show significant biological activity, making them valuable in tissue/dental repair. Silver-incorporated MBG exhibits promising antibacterial effects against various bacteria; copper ions are crucial in regulating angiogenesis signals.

Radiology insights into Petersen's hernia complication of post Roux-en-Y gastric bypass.

Following gastrojejunostomy in Roux-en-Y gastric bypass (RYGB), the mesentery is susceptible to Petersen's hernia due to a mesenteric gap created between the alimentary limb, transverse mesocolon, and retroperitoneum. Although the Petersen's hernia is a rare complication, it has increased due to the widespread adoption of gastric bypass surgeries for weight management and gastric cancer resections. Computed tomography (CT) is commonly used to evaluate suspected cases.