[Adsorption of Tetracycline in Composite-polluted Water by Biochar from Industrial Production].

Compared to the laboratory preparation of biochar, there is less research on the adsorption of antibiotics by industrial production of biochar in water. In this study, three types of industrial production biochar （peanut shell biochar, sludge biochar, and perishable waste biochar） were selected, and their adsorption performance for tetracycline in composite-polluted water was systematically studied. The results indicated that the Freundlich equation could well fit the adsorption isotherms of the three types of biochar for tetracycline.

[Spatial-temporal Variations and Driving Factors Analysis of Total Nitrogen Concentration in the Haihe River Basin from 2018 to 2022].

The Beijing-Tianjin-Hebei （Jing-Jin-Ji） Region is home to the most acute economic, resource, and environmental conflicts in the Bohai Sea region, and the rivers entering the sea carry abundant total nitrogen （TN） input into the Bohai Bay, which is the main land-based input causing eutrophication of the bay. The Haihe River Basin in the Jing-Jin-Ji Region was divided into 112 （2018-2019） and 187 （2020-2022） control units, and the spatial and temporal variations in TN concentration in the surface water of the Haihe River Basin in the Jing-Jin-Ji Region were systematically analyzed from 2018 to 2022 by combining the Euclidean distance analysis method and the K-means clustering analysis method. The results showed that the annual average concentration of TN in the region showed a trend of decreasing （2018-2020） and then increasing （2021-2022）, in which the concentration of TN increased significantly from June 2021 to June 2022.

Dynamic Detection of the E3-PROTAC-Target Protein Ternary Complex and Bimolecular Fluorescence Complementation.

Proteolysis-targeting chimeras (PROTACs) have played an important role in the development of protein-targeted degradation drugs. However, effective tools are urgently required for the further development and validation of PROTACs. We developed a high-potency reporter (AKT-PROTAC-Reporter; APR) for PROTACs that specifically targets AKT.

Two secretory T2 RNases from a fungal pathogen target distinct insect cell transmembrane proteins to cause cytotoxicity.

Fungal pathogens produce secretory ribonuclease (RNase) T2 proteins during infection, which contribute to fungal virulence via their enzyme functions in degradation of host cell RNA. However, the details of those proteins entering the host cells are unclear. Our previous study demonstrated that the two secretory RNase T2 members, BbRNT2 and BbTrv, produced by the insect fungal pathogen Beauveria bassiana, caused cytotoxic damage to insect cells and contributed to fungal virulence.

Copper doped magnetic vortex nanoring based nanotherapeutics for bacterial infection tri-therapy: interplay of magnetic hyperthermia, chemodynamic therapy and photothermal therapy.

Infectious bacteria pose an increasing threat to public health, and hospital-acquired bacterial infections remain a significant challenge for wound healing. In this study, we developed an advanced nanoplatform utilizing copper doped magnetic vortex nanoring coated with polydopamine (Cu-MVNp) based nanotherapeutics for bacterial infection tri-therapy. This multifunctional nanoplatform exhibits remarkable dual-stimulus thermogenic capabilities and Fenton-like peroxidase activity.