Secondary metabolites of Alternaria alternate appraisal of their SARS-CoV-2 inhibitory and anti-inflammatory potentials.

This study identifies the secondary metabolites from Alternaria alternate and evaluates their ACE-2: Spike RBD (SARS-CoV-2) inhibitory activity confirmed via immunoblotting in human lung microvascular endothelial cells. In addition, their in vitro anti-inflammatory potential was assessed using a cell-based assay in LPS-treated RAW 264.7 macrophage cells.

Clinical Characteristics of Snakebite Envenomings in Taiwan.

Snakebite envenomings continue to represent a major public health concern in Taiwan because of the presence of various venomous snakes whose habitats intersect with human activities. This review provides a comprehensive analysis of the clinical characteristics, complications, and management strategies associated with snakebite envenomings in Taiwan. Taiwan is inhabited by six principal venomous snakes: , , , , , and , each presenting distinct clinical challenges.

The reaction mechanisms of ethylene oxide and propylene oxide with food Simulants: Based on experiments and computational analysis.

Ethylene oxide (EO) and propylene oxide (PO) are widely used as sterilizing agents in the food industry. However, their residues in food packaging can migrate into food and react with it, affecting the accuracy of residue detection in food. This study aims to explore the reaction mechanisms between EO and PO and aqueous food simulants using both experimental and computational methods.

Meibomian gland alterations in allergic conjunctivitis: insights from a novel quantitative analysis algorithm.

Purpose: To investigate the changes in meibomian gland (MG) structure in allergic conjunctivitis (AC) patients using an intelligent quantitative analysis algorithm and to explore the relationship between these changes and clinical parameters.

Methods: A total of 252 eyes from patients with AC and 200 eyes from normal controls were examined. Infrared meibography was performed using the non-contact mode of the Keratograph 5M.

Eating "rubbish"? Exploring the herbal secrets of "Laji-He," a traditional herbal rice snack from southern China.

Background: Laji-He is a traditional rice-based snack from the Beibu Gulf region in southern China. In the Beibu Gulf region, "Laji-He" (literally "garbage He") signifies the removal of toxins from the body, making it a truly "green" food. Laji-He holds essential cultural and medicinal value, incorporating various medicinal plants into its preparation.