Topical Application of in Wound Healing: Recent Insights into Mechanisms and Clinical Efficacy.

, widely known as , is a traditional herb celebrated for its benefits in skin health and wound healing. Recent research has provided new insights into its efficacy, particularly through topical applications. This review highlights the plant's mechanisms, focusing on its active compounds such as asiaticoside, madecassoside, asiatic acid, and madecassic acid, which enhance collagen synthesis, modulate inflammation, and offer antioxidant protection.

Value of [F]FDG PET/CT parameters of the primary tumor in assessing overall survival in NSCLC patients with cN1-cN3 lymph nodes involvement.

Background: The aim of this retrospective study was to assess the value of F-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography ([F]FDG PET/CT parameters in cN1-cN3 non-small cell lung cancer (NSCLC) patients.

Materials And Methods: 59 consecutive patients (35 M, 24 F) with NSCLC who underwent pretreatment [F]FDG PET/CT were enrolled to this study. Several primary tumor PET parameters, including the maximum and mean standardized uptake value (SUV and SUV, the metabolic active tumor volume (MTV) and the total lesion glycolysis (TLG = MTVxSUV), were extracted and analysed.

Electrospun Nanofibers Loaded with Marigold Extract Based on PVP/HPβCD and PCL/PVP Scaffolds for Wound Healing Applications.

Marigold flower is a traditionally used plant material topically applied on the skin due to its anti-inflammatory properties and antibacterial activity. This potential of action justifies the implementation of marigold extract in nanofiber scaffolds based on poly-vinylpyrrolidone/hydroxypropyl-β-cyclodextrin (PVP/HPβCD) and polycaprolactone/polyvinylpyrrolidone (PCL/PVP) obtained by electrospinning for wound treatment. Using SEM, the morphology of electrospun scaffolds showed a fiber diameter in the range of 298-527 nm, with a uniform and bead-free appearance.

Chitosan-Based Hydrogels for Controlled Delivery of Asiaticoside-Rich Extracts with Wound Healing Potential.

extract is a valued plant material with known anti-inflammatory and anti-microbiological properties. Using the Design of Experiment (DoE) approach, it was possible to obtain an optimized water/alcoholic extract from , which allowed the preparation of the final material with biological activity in the wound healing process. Studies on the novel applications of in conjunction with the multifunctional chitosan carrier have been motivated by the plant's substantial pharmacological activity and the need to develop new and effective methods for the treatment of chronic wounds.