Hydrogen sulfide (HS) and inorganic polysulfides are important signaling molecules; however, little is known about their role in adipose tissue. We examined the effect of HS and polysulfides on insulin sensitivity of the adipose tissue in rats. Plasma glucose, insulin, non-esterified fatty acids, and glycerol were measured after administration of HS and the polysulfide donors, NaS and NaS, respectively.
View Article and Find Full Text PDFHydrogen sulfide (HS) and inorganic polysulfides are important signaling molecules; however, little is known about their role in the adipose tissue. We examined the effect of HS and polysulfides on adipose tissue lipolysis. HS and polysulfide production by mesenteric adipose tissue explants in rats was measured.
View Article and Find Full Text PDFCyclosporine A (CsA) is an immunosuppressive drug used in transplantation and treatment of autoimmune diseases. Experimental studies revealed impairments in liver function and morphology among cyclosporine-treated animals. The aim of the study was to evaluate hepatoprotective activity of peroxisome-proliferator-activated receptors γ (PPARγ) ligands: rosiglitazone and 15-deoxy-Δ-prostaglandin J (PGDJ2) on CsA-induced hepatotoxicity in experimental animals.
View Article and Find Full Text PDFUnlabelled: Neutrophil-lymphocyte count ratio (NLCR) is a recognized prognostic marker for renal, lung or colorectal carcinomas. The aim of the present study was to determine whether the preoperative value of NLCR might serve as a predictive marker for glial tumors' grading.
Methods: The retrospective analysis of NLCR was performed in neurosurgical patients treated for glial brain tumors.
Hematopoietic Stem Cell Transplantation (HSCT) is a very important life-saving procedure to treat many disorders. In August 2014, there were more than 24.5 million donor registered in the Worldwide Bone Marrow Donor Register.
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