Dextromethorphan/Bupropion: A Novel Treatment for Patients With Major Depressive Disorder.

Background: Major depressive disorder (MDD) affects millions of people and is the leading cause of disability worldwide. Patients report decreased quality of life and ability to perform activities of daily living. It is estimated that the current standard of care, which includes pharmacologic therapy with a selective serotonin reuptake inhibitor, is effective in 40%-60%.

SCLEROMYXEDEMA ASSOCIATED WITH MACULAR EDEMA AND RETINAL HEMORRHAGE.

Purpose: We discuss a case of macular edema and retinal hemorrhage associated with scleromyxedema.

Methods: A case report is presented.

Results: A 64-year-old man with history of deep vein thrombosis and pulmonary embolism presented with new-onset rash in the setting of switching anticoagulation treatments.

Development of trauma systems in Europe-reports from England, Germany, the Netherlands, and Spain.

Major trauma systems have evolved in many European countries and have resulted in improved care in terms of mortality and morbidity. Many of the systems have similar history, with reports of either poor services, or a single disaster, driving change of policy and set up. We report on 4 European systems, looking at the background, set up and some of the results.