Disease Investigations & Initial Response: Considerations from Policy to Farm.

Transboundary animal disease (TAD) investigations are conducted routinely across the United States to rule out diseases of significant economic, trade, and/or food security importance. Established protocols exist for TAD investigations and disease response based on national and international policy; however, now more than ever, private practitioners may be called upon to assist in these investigations and response activities and may play an important role in communications, sample collection, and disease surveillance. Successful implementation of disease investigation and response, with or without vaccination, requires a collaborative effort between regulatory officials, industry groups, private practitioners, and producers.

Temperature affects viral kinetics and vectorial capacity of Aedes aegypti mosquitoes co-infected with Mayaro and Dengue viruses.

Background: Increasing global temperatures and unpredictable climatic extremes have contributed to the spread of vector-borne diseases. The mosquito Aedes aegypti is the main vector of multiple arboviruses that negatively impact human health, mostly in low socioeconomic areas of the world. Co-circulation and co-infection of these viruses in humans have been increasingly reported; however, how vectors contribute to this alarming trend remains unclear.

Development of circulating isolates of Plasmodium falciparum is accelerated in Anopheles vectors with reduced reproductive output.

Anopheles gambiae and its sibling species Anopheles coluzzii are the most efficient vectors of the malaria parasite Plasmodium falciparum. When females of these species feed on an infected human host, oogenesis and parasite development proceed concurrently, but interactions between these processes are not fully understood. Using multiple natural P.