From classroom to community: A college of pharmacy's faculty and student participation at a harm reduction coalition.

Background And Purpose: Harm reduction is a paradigm that promotes safer drug consumption to maximize individuals' overall wellbeing. Equipping pharmacy faculty and students to engage in harm reduction can play a key role in addressing substance use disorders and facilitating meaningful educational experiences.

Educational Activity And Setting: Within the context of a 5-week ambulatory care advanced pharmacy practice experience (APPE), an APPE faculty preceptor and students engaged a harm reduction coalition with two primary objectives: street outreach initiatives and packaging of safer drug using kits.

Secondhand cannabis smoke exposure and respiratory symptoms among adults living in a state with legalized medical cannabis with limited smoke-free protections.

Background: Little is known about the demographic and health correlates of secondhand cannabis smoke (SHCS) exposure, despite increased availability and use of cannabis across the U.S. This study examined the prevalence and correlates of SHCS exposure in a sample of N=5,410 adults living in Oklahoma and the association of SHCS exposure with self-reported respiratory problems.

The Impact of Childhood Trauma on the Negative Symptoms of Schizophrenia.

Schizophrenia is a debilitating mental health disorder that imposes profound economic, societal, and personal burdens. The negative symptoms of schizophrenia ( i.e.

Adult microglial TGFβ1 is required for microglia homeostasis via an autocrine mechanism to maintain cognitive function in mice.

While TGF-β signaling is essential for microglial function, the cellular source of TGF-β1 ligand and its spatial regulation remains unclear in the adult CNS. Our data supports that microglia but not astrocytes or neurons are the primary producers of TGF-β1 ligands needed for microglial homeostasis. Microglia-Tgfb1 KO leads to the activation of microglia featuring a dyshomeostatic transcriptome that resembles disease-associated, injury-associated, and aged microglia, suggesting microglial self-produced TGF-β1 ligands are important in the adult CNS.

How Pharmacy Students Feel about an HIV Pre-Exposure Prophylaxis Advertising Campaign.

: This activity prompted pharmacy students to analyze a Los Angeles Lesbian, Gay, Bisexual, and Transgender (LA LGBT) Center-generated "F**k w/out fear" HIV pre-exposure prophylaxis (PrEP) billboard campaign. Students shared their thoughts after viewing the billboard (initial reactions); if the billboard was offensive (Yes/No); if the billboard effectively raises awareness about sexually transmitted infection (STI) prevention (Yes/No); and if they believed pharmacy school is an appropriate place to discuss this topic (Yes/No). Students also provided open-ended responses directed to the campaign's developer(s).