Publications by authors named "K Walls"
Article Synopsis
- Arylamine-acetyltransferase 2 (NAT2) is implicated in drug metabolism and may be linked to dyslipidemia and cardiometabolic disorders, highlighting its role in metabolic health.
- Recent research has indicated that NAT2 expression is influenced by glucose and insulin levels, and it is co-expressed with liver nuclear receptors that impact glucose and lipid balance.
- The study tested whether various hepatic nuclear receptors (FXR, PXR, LXR, PPARα) can regulate NAT2 expression in human liver cells, finding that none significantly affected NAT2 levels, suggesting the need for further investigation into its transcriptional regulation.
Article Synopsis
- The skin is the largest organ and skin infections can seriously affect health and self-image, which prompted a systematic review that updates treatment strategies for various skin infections prevalent in resource-limited settings.
- This review builds on a previous one from 2019 and incorporates new data on conditions like atopic dermatitis and head lice to revise the Australian National Healthy Skin guidelines.
- A thorough search of medical literature from 1960 to 2022 identified 68 studies focusing on the treatment of specific skin infections among Indigenous populations in lower-income areas, leading to key recommendations based on the evidence gathered.
Calaway, C, Walls, K, Levitt, H, Caplan, J, Mann, B, Martinez, K, Gastaldo, R, Haq, I, and Signorile, JF. Velocity-based-training frequency impacts changes in muscle morphology, neuromuscular performance, and functional capability in persons with Parkinson's disease. J Strength Cond Res 39(1): 99-106, 2025-Velocity-based training (VBT) positively impacts muscle morphology and performance in persons with Parkinson's disease (PD); however, optimal training frequencies for VBT in patients with PD remain undetermined.
View Article and Find Full Text PDFHeterocyclic Amines Disrupt Lipid Homeostasis in Cryopreserved Human Hepatocytes.
Cardiovasc Toxicol
August 2024
Metabolic dysfunction associated-steatotic liver disease (MASLD)/metabolic dysfunction-associated steatohepatitis (MASH) is the liver manifestation of metabolic syndrome, which is characterized by insulin resistance, hyperglycemia, hypertension, dyslipidemia, and/or obesity. Environmental pollutant exposure has been recently identified as a risk factor for developing MASH. Heterocyclic amines (HCAs) are mutagens generated when cooking meat at high temperatures or until well-done.
View Article and Find Full Text PDF