The associations of long-term physical activity in adulthood with later biological ageing and all-cause mortality - a prospective twin study.

Objectives: The association between leisure-time physical activity (LTPA) and a lower risk of mortality is susceptible to bias from multiple sources. We investigated the potential of biological ageing to mediate the association between long-term LTPA and mortality and whether the methods used to account for reverse causality affect the interpretation of this association.

Methods: Study participants were twins from the older Finnish Twin Cohort (n = 22,750; 18-50 years at baseline).

Impact of distance from liver transplant centre on outcomes following liver transplantation: an Australian single-centre study.

Background: Access to liver transplantation (LT) is affected by geographic disparities. Higher waitlist mortality is observed in patients residing farther from LT centres, but the impact of distance on post-LT outcomes is unclear.

Aims: To evaluate whether the distance LT recipients reside from their LT centre affects graft and patient outcomes.

Conceptualising, operationalising and utilising equity, diversity and inclusion in clinical trials: a scoping review.

Introduction: Equity, diversity and inclusion (EDI) are social constructs which when used in clinical trials help generate the highest quality evidence for interventions in the populations most likely to benefit. However, the incorporation of these constructs in clinical trials is unclear and inconsistent. This scoping review sought to understand how EDI is applied in clinical trials.

Computed tomographic findings in 25 cats with ear canal neoplasia.

Computed tomography is commonly used to evaluate feline otic disease; however, published studies characterizing the CT appearance of ear canal neoplasia are limited. The purpose of this multicenter, retrospective, secondary analysis, cross-sectional study was to describe the CT features of histopathologically confirmed feline ear canal neoplasia. The CT studies of 25 cats with ear canal neoplasia were prospectively scored by consensus of two veterinary radiologists.

Genomic analyses of Streptococcus uberis reveal high diversity but few antibiotic resistance genes.

This study aimed to investigate the diversity of milk isolates of Streptococcus uberis from Swedish dairy cows with mastitis, focusing on antibiotic resistance and virulence genes. We analyzed 115 S. uberis isolates using whole genome sequencing revealing a high level of diversity.