Experiences in the tourism industry after spinal cord injury: A scoping review.

Context: Despite being important for health and wellbeing, people with a disability engage in tourism significantly less than people who are non-disabled. It is important to understand why this is occurring so that we can set an agenda toward accessible tourism.

Objective: To understand the tourism experiences and needs of people living with spinal cord injury.

The potential of baicalin to enhance neuroprotection and mitochondrial function in a human neuronal cell model.

Baicalin is a flavone glycoside derived from flowering plants belonging to the Scutellaria genus. Previous studies have reported baicalin's anti-inflammatory and neuroprotective properties in rodent models, indicating the potential of baicalin in neuropsychiatric disorders where alterations in numerous processes are observed. However, the extent of baicalin's therapeutic effects remains undetermined in a human cell model, more specifically, neuronal cells to mimic the brain environment in vitro.

Network-based drug repurposing for schizophrenia.

Despite recent progress, the challenges in drug discovery for schizophrenia persist. However, computational drug repurposing has gained popularity as it leverages the wealth of expanding biomedical databases. Network analyses provide a comprehensive understanding of transcription factor (TF) regulatory effects through gene regulatory networks, which capture the interactions between TFs and target genes by integrating various lines of evidence.

Amyloid beta 42 alters cardiac metabolism and impairs cardiac function in male mice with obesity.

There are epidemiological associations between obesity and type 2 diabetes, cardiovascular disease and Alzheimer's disease. The role of amyloid beta 42 (Aβ) in these diverse chronic diseases is obscure. Here we show that adipose tissue releases Aβ, which is increased from adipose tissue of male mice with obesity and is associated with higher plasma Aβ.