Publications by authors named "K Wakahara"
Background: Multiple first-line treatment options have been developed for advanced non-small cell lung cancer (NSCLC) in each subgroup determined by predictive biomarkers, specifically driver oncogene and programmed cell death ligand-1 (PD-L1) status. However, the methodology for optimal treatment selection in individual patients is not established. This study aimed to develop artificial intelligence (AI)-based personalized survival prediction model according to treatment selection.
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- Blood eosinophil count is a significant biomarker for managing chronic obstructive pulmonary disease (COPD), but its precise role in the disease still needs further exploration.
- A study with 93 COPD patients showed that 19.3% had eosinophilic COPD, and while eosinophil counts correlated with some blood parameters, they also indicated lung structural changes related to the disease.
- The findings suggest that elevated eosinophils may contribute to alveolar damage and thickening of airway walls in COPD patients lacking asthma, highlighting the need for further research on this inflammation type in COPD.
Good adherence to an inhaled medication protocol is necessary for the management of asthma and chronic obstructive pulmonary disease (COPD), and several interventions to improve adherence have been reported. However, the impact of patient life changes and psychological aspects on treatment motivation is obscure. Here, we investigated changes in inhaler adherence during the COVID-19 pandemic and how lifestyle and psychological changes affected it.
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