Analysis of health recommendations using longitudinal quality of life data: QoL@TbA - A transformer-based approach.

Health recommendation systems suggest behavioral modifications to improve quality of life. However, current approaches do not facilitate the generation or examination of such recommendations considering the multifeature longitudinal evolution of behaviors. This paper proposes the use of a deep learning transformer-based model that allows the analysis of recommendations for behavior changes.

Improving completion rates of patient-reported outcome measures in cancer clinical trials: Scoping review investigating the implications for trial designs.

Background: Patient-reported outcomes (PROs) play a crucial role in cancer clinical trials. Despite the availability of validated PRO measures (PROMs), challenges related to low completion rates and missing data remain, potentially affecting the trial results' validity. This review explored strategies to improve and maintain high PROM completion rates in cancer clinical trials.

Reverse Engineering of Digital Measures: Inviting Patients to the Conversation.

Background: Digital measures offer an unparalleled opportunity to create a more holistic picture of how people who are patients behave in their real-world environments, thereby establishing a better connection between patients, caregivers, and the clinical evidence used to drive drug development and disease management. Reaching this vision will require achieving a new level of co-creation between the stakeholders who design, develop, use, and make decisions using evidence from digital measures.

Summary: In September 2022, the second in a series of meetings hosted by the Swiss Federal Institute of Technology in Zürich, the Foundation for the National Institutes of Health Biomarkers Consortium, and sponsored by Wellcome Trust, entitled "Reverse Engineering of Digital Measures," was held in Zurich, Switzerland, with a broad range of stakeholders sharing their experience across four case studies to examine how patient centricity is essential in shaping development and validation of digital evidence generation tools.

Behaviour recommendations with a deep learning model and genetic algorithm for health debt characterisation.

Human behaviour is a dense longitudinal multi-featured measure that directly impacts the health of individuals in the short and long terms. Therefore, issues usually emerge from the insistence on performing risky behaviours, such as smoking or eating fast foods, which continuously increase the gap between current and beneficial health states. This paper introduces the term "health debt" as an economic metaphor to represent the quantification of this gap in domains such as sleep, contributing to physical and mental health states.