Characteristics and predictors of major occupational injuries in Korean farmers.

Farmers are exposed to various risks due to the nature of the agricultural environment, and occupational injuries occur consistently. Hence, this study aimed to investigate the characteristics and predictors of major non-fatal occupational injuries among farmers by analysing incidents of non-fatal occupational injuries resulting in at least 1 day off work using the Korean Agricultural Workers' Occupational Disease and Injury Survey data. Multivariate logistic regression was performed to identify the predictors of agricultural occupational injuries, and the results indicated that the risk for non-fatal injuries was higher among older individuals, individuals with pre-existing physical limitations and individuals who use agricultural machinery.

Novel Less Toxic, Lymphoid Tissue-Targeted Lipid Nanoparticles Containing a Vitamin B5-Derived Ionizable Lipid for mRNA Vaccine Delivery.

Following their approval by the Food and Drug Administration, lipid nanoparticles (LNPs) have emerged as promising tools for delivering mRNA vaccines and therapeutics. Ionizable lipids are among the essential components of LNPs, as they play crucial roles in encapsulating mRNA and facilitating its release into the cytosol. In this study, 17 innovative ionizable lipids using vitamin B5 are designed as the core structure, aiming to reduce toxicity, to maintain vaccine efficiency, and to ensure synthetic feasibility.

Discovery of Kuraridin as a Potential Natural Anti-Melanogenic Agent: Focusing on Specific Target Genes and Multidirectional Signaling Pathways.

Abnormal melanogenesis upon UV exposure causes excessive oxidative stress, leading to hyperpigmentation disorders. As a key rate-limiting enzyme in melanogenesis, tyrosinase is considered a primary target for depigmenting agents. is used as a food and in traditional medicine as a valuable source of prenylated flavonoids.

Risk Factors for Musculoskeletal Disorders in Korean Farmers: Survey on Occupational Diseases in 2020 and 2022.

Background/objectives: This study investigated factors influencing the prevalence of musculoskeletal disorders (MSDs) resulting from agricultural work, utilizing the 2020 and 2022 occupational disease survey data collected by the Rural Development Administration. The combined data from these years indicated a 6.02% prevalence of MSDs, reflecting a significant class imbalance in the binary response variables.

Morphometric analysis of the hard palate in sex estimation among koreans using three-dimensional computed tomography.

Accurate sex estimation is crucial for comprehensive analysis of the biological profiles of unidentified human skeletal remains. However, there is a notable lack of research specifically addressing the morphometrics of the hard palate. Therefore, this study aimed to derive discriminant equations using the hard palate and assess their applicability for sexing partial skeletal remains in a contemporary Korean population.