A double-blind, randomized, placebo-controlled study to evaluate the efficacy of Oxybutynin Chloride Extended-Release tablets on the double-J stent related symptoms following uncomplicated ureteroscopic lithotripsy.

To evaluate the effects of Oxybutynin Chloride Extended-Release Tablets (Oxbu) on double-J stent-related symptoms following uncomplicated ureterosocpic lithotripsy (URSL). This is a double-blind, randomized, placebo-controlled study with a total of 120 subjects with ureteral calculi receiving double-J stent insertion following URSL. Subjects who meet the inclusion and exclusion criteria will be randomly assigned to Oxbu or placebo group.

Impact of tea and coffee consumption during pregnancy on children's cognitive development.

Evidence on the association between maternal tea/coffee consumption and children's cognitive development is limited. This study included 1423 mother-child pairs from the Chinese National Birth Cohort (CNBC). Maternal tea/coffee consumption status was collected in the 1st, 2nd and 3rd trimesters of pregnancy.

Cigarette smoke-induced epithelial cell ferroptosis promotes neutrophilic inflammation in patients with nasal polyps.

Background: Regulation of epithelial cell death has emerged as a key mechanism maintaining immune homeostasis in the airway. However, the mechanisms governing epithelial cell survival in nasal polyps (NPs) remains poorly understood.

Objective: To investigate the ferroptosis of nasal epithelial cell and its implications in the pathogenesis of NPs.

Rice bran protein fibril and chitin nanofiber complexes as a new material for fat substitution and saltiness enhancement.

Rice bran protein fibrils (RBPFs) and chitin nanofibers (CNFs) have great untapped application potential in fat and salt reduction. The present study aims to prepare RBPF-CNF complexes at the optimum conditions and investigate their structures and physicochemical properties. RBPFs and CNFs formed better fiber structures with the higher viscosity and saltiness when heated for 10 h and ultrasound treated for 40 min, respectively.

The Role of Choroid Plexus in Hydrocephalus from the Perspective of Structure and Function: a Therapeutic Target.

Hydrocephalus is one of the most common neurological diseases, characterized by abnormal excessive accumulation of cerebrospinal fluid (CSF) in the ventricular system. Its pathophysiological mechanism is believed to be related to the imbalance of CSF circulation and homeostasis. As the main source of CSF secretion, the choroid plexus is closely related to hydrocephalus.