Royal Jelly Acid Alleviates Diet-Induced Hyperlipidemia through Regulation of Oxidative Stress and Tryptophan Metabolism.

Royal jelly acid is a unique unsaturated fatty acid isolated from royal jelly. Recently, royal jelly acid was proposed to have potential therapeutic effects on hyperlipidemia. However, its effect on hyperlipidemia and the underlying molecular mechanism remains unclear.

Highly Efficient and Stable Mn-CoNiO Electrocatalysts for Alkaline Water Electrolysis: Atomic Doping Strategy for Enhanced OER and HER Performance.

Water electrolysis for hydrogen production has garnered significant attention due to its advantages of high efficiency, environmental friendliness, and abundant resources. Developing cost-effective, efficient, and stable materials for water electrolysis is therefore crucial. In this work, we synthesized a series of highly efficient multifunctional Mn-CoNiO electrocatalysts through an atomic doping strategy for alkaline electrocatalysts.

GluOC Induced SLC7A11 and SLC38A1 to Activate Redox Processes and Resist Ferroptosis in TNBC.

Background/objectives: Ferroptosis, a type of programmed cell death, is mainly associated with disruptions in iron metabolism, imbalances in the amino acid antioxidant system, and the build-up of lipid peroxides. Triple-negative breast cancer (TNBC) has a dismal prognosis. Since activating ferroptosis can suppress breast cancer cell proliferation, it holds promise as a novel therapeutic target for breast cancer patients.

Vitality is associated with systemic inflammation in cystic fibrosis adults on elexacaftor/tezacaftor/ivacaftor.

Fatigue is common among adults with cystic fibrosis (awCF) and may be associated with systemic inflammation. This study examines systemic inflammation, measured by C-reactive protein (CRP), and fatigue, assessed using the Cystic Fibrosis Questionnaire-Revised (CFQ-R) vitality domain, in individuals initiating elexacaftor/tezacaftor/ivacaftor (ETI) therapy. In a cohort of 61 awCF from St.

gen. nov., sp. nov., a novel halophilic bacterium isolated from tidal flat sediment.

A novel bacterial strain, MJW-29, was isolated from tidal flat sediment in Gochang, Republic of Korea. The isolate is Gram-stain-negative, facultatively anaerobic, gliding motile and short rods. The strain MJW-29 is oxidase and catalase positive.